Study of Zifibancimig in Participants With Neovascular Age-related Macular Degeneration (NCT04567303)
A Three-part, Phase I/II Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of Zifibancimig Following Intravitreal Administration of Multiple Ascending Doses and Continuous Delivery From the Port Delivery in Patients With Neovascular Age-related Macular Degeneration
🩺 Plain-English Summary (8th-Grade Level)
This is a first in-human study to investigate the safety, tolerability and efficacy of zifibancimig administered through intravitreal (IVT) injections and via the port delivery (PD) implant in participants with neovascular age-related macular degeneration (nAMD).
Who can join: Review the eligibility criteria below.
Location: Barnet Dulaney Perkins Eye Center — Mesa, Arizona
Age range: 50 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (38 Sites)
Showing the first 25 of 38 sites.
- Barnet Dulaney Perkins Eye Center — Mesa, Arizona
- Associated Retina Consultants — Phoenix, Arizona
- The Retina Partners — Encino, California
- Retinal Consultants Med Group — Sacramento, California
- Orange County Retina Med Group — Santa Ana, California
- Southwest Retina Consultants — Durango, Colorado
- Retina Vitreous Assoc of FL — St. Petersburg, Florida
- Southern Vitreoretinal Assoc — Tallahassee, Florida
- Retina Associates of Florida, LLC — Tampa, Florida
- Southeast Retina Center — Augusta, Georgia
- University Retina and Macula Associates, PC — Oak Forest, Illinois
- Maine Eye Center — Portland, Maine
- Johns Hopkins Med — Baltimore, Maryland
- Retina Group of Washington — Chevy Chase, Maryland
- Cumberland Valley Retina Consultants — Hagerstown, Maryland
- Foundation for Vision Research — Grand Rapids, Michigan
- Associated Retinal Consultants — Royal Oak, Michigan
- VitreoRetinal Surgery, PLLC. — Saint Louis Park, Minnesota
- The Retina Institute — St Louis, Missouri
- Sierra Eye Associates — Reno, Nevada
- Envision Ocular, LLC — Bloomfield, New Jersey
- Retina Vit Surgeons/Central NY — Liverpool, New York
- Duke Eye Center — Durham, North Carolina
- Graystone Eye — Hickory, North Carolina
- OSU Eye Physicians & Surgeons — Columbus, Ohio
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.