DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE) (NCT04567420)

🧪 Interventions in This Study

• Palbociclib (DRUG)
• Fulvestrant (DRUG)
• Adjuvant Therapy (DRUG)

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (19 Sites)

• University of Arizona Cancer Center — Tucson, Arizona
• USC/Norris Comprehensive Cancer Center — Los Angeles, California
• Cedars-Sinai Medical Center — Los Angeles, California
• University of Colorado Cancer Center — Aurora, Colorado
• Intermountain — Golden, Colorado
• Yale Cancer Center — New Haven, Connecticut
• Winship Cancer Institute of Emory University — Atlanta, Georgia
• Louisiana State University Health Sciences Center- New Orleans — New Orleans, Louisiana
• Cancer Partners of Nebraska — Lincoln, Nebraska
• New Mexico Cancer Care Alliance — Albuquerque, New Mexico
• Icahn School of Medicine at Mount Sinai — New York, New York
• Stony Brook University Cancer Center — Stony Brook, New York
• The Ohio State University Wexner Medical Center James Cancer Hospital — Columbus, Ohio
• Stephenson Cancer Center — Oklahoma City, Oklahoma
• Oregon Health and Science University — Portland, Oregon
• PRiSMs Group — Laredo, Texas
• Virginia Cancer Institute — Richmond, Virginia
• Swedish Cancer Institute — Seattle, Washington
• University of Wisconsin Clinical Science Center — Madison, Wisconsin

💰 Cost, Insurance & Patient Rights

• 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
• Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
• Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

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💡 How to Participate

1. Check the checklist above to see if you may qualify.
2. Review the official NIH record below to find the coordinating site.
3. Ask about the visit schedule, what is covered at no cost, and any travel support.
4. Confirm with your own doctor before making a decision.