๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-05-28

Atrasentan in Patients With Proteinuric Glomerular Diseases (NCT04573920)

A Phase 2, Open-Label, Basket Study of Atrasentan in Patients With Proteinuric Glomerular Diseases

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Novartis Pharmaceuticals

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The AFFINITY Study is a phase 2, open-label, basket study to evaluate the efficacy and safety of atrasentan in patients with proteinuric glomerular disease who are at risk of progressive loss of renal function.

Who can join: Review the eligibility criteria below.

Location: Kidney Disease Medical Group โ€” Glendale, California

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (33 Sites)

Showing the first 25 of 33 sites.

  • Kidney Disease Medical Group โ€” Glendale, California
  • Academic Medical Research Institute โ€” Los Angeles, California
  • North America Research Institute โ€” San Dimas, California
  • Stanford U School Of Medicine โ€” Stanford, California
  • Colorado Kidney Care Nephrology โ€” Denver, Colorado
  • Northwest Louisiana Nephrology Research โ€” Shreveport, Louisiana
  • Tufts Medical Center โ€” Boston, Massachusetts
  • Uni of Minnesota Hos and Clinics โ€” Minneapolis, Minnesota
  • DaVita Clinical Research โ€” Las Vegas, Nevada
  • Mountain Kidney And Hyper Associa โ€” Asheville, North Carolina
  • Brookview Hills Research Assoc โ€” Winston-Salem, North Carolina
  • Baylor Scott and White โ€” Dallas, Texas
  • Prolato Clinical Research Center โ€” Houston, Texas
  • Milwaukee Nephrologists SC โ€” Wauwatosa, Wisconsin
  • Novartis Investigative Site โ€” Gosford, New South Wales
  • Novartis Investigative Site โ€” Herston, Queensland
  • Novartis Investigative Site โ€” Clayton, Victoria
  • Novartis Investigative Site โ€” Reservoir, Victoria
  • Novartis Investigative Site โ€” St Albans, Victoria
  • Novartis Investigative Site โ€” St Leonards,
  • Novartis Investigative Site โ€” Roma, RM
  • Novartis Investigative Site โ€” Cheonan, Chungcheongnam-do
  • Novartis Investigative Site โ€” Anyang-si, Gyeonggi-do
  • Novartis Investigative Site โ€” Seoul, Korea
  • Novartis Investigative Site โ€” Seoul,

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All IgA Nephropathy clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—