๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-08-08

Lung Structure-Function In Survivors of Mild and Severe COVID-19 Infection (NCT04584671)

Lung Structure-Function In SurVivors of Mild and SEvere COVID-19 Infection: 129Xe MRI and CT For Rapid Evaluations and NExt-wave Healthcare Planning

๐Ÿ”ต Active, Not Recruiting Interventional Protocol ๐Ÿ“Š Observational Clinical Research Sponsor: Western University, Canada

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is a longitudinal study of the long-term impact of COVID-19 on the lungs. Participants will be followed over a period of up to 4 years and impacts of COVID-19 on the lungs will be measured with magnetic resonance imaging (MRI) using hyperpolarized xenon-129, pulmonary function tests, exercise capacity, computed tomography imaging and questionnaires.

Who can join: Review the eligibility criteria below.

Location: Department of Medicine (Respirology), McMaster University โ€” Hamilton, Ontario

Age range: 18 Years to 80 Years

๐Ÿงช Interventions in This Study

  • Hyperpolarized Xenon-129 MRI of the lungs (DIAGNOSTIC_TEST)
  • Computed Tomography (CT) (DIAGNOSTIC_TEST)
  • Pulmonary Function Tests (PFT) (DIAGNOSTIC_TEST)
  • Six Minute Walk Test (6MWT) (DIAGNOSTIC_TEST)
  • Sputum analysis (DIAGNOSTIC_TEST)
  • Blood analysis (DIAGNOSTIC_TEST)
  • Questionnaires (OTHER)

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (1 Sites)

  • Department of Medicine (Respirology), McMaster University โ€” Hamilton, Ontario

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Covid19 clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—