๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-06-24

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer (NCT04614103)

A Phase 2 Multicenter Study of Autologous Tumor Infiltrating Lymphocytes (TIL or LN-145) in Patients With Metastatic Non-Small-Cell Lung Cancer

๐ŸŸข Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Iovance Biotherapeutics, Inc.

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is a prospective, open-label, multi-cohort, non-randomized, multicenter phase 2 study evaluating LN-145 in patients with metastatic non-small-cell lung cancer

Who can join: Review the eligibility criteria below.

Location: Banner Health MD Anderson โ€” Gilbert, Arizona

Age range: 18 Years to 70 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (71 Sites)

Showing the first 25 of 71 sites.

  • Banner Health MD Anderson โ€” Gilbert, Arizona
  • Sylvester Comprehensive Cancer Center โ€” Miami, Florida
  • H Lee Moffitt Cancer Center and Research Institute โ€” Tampa, Florida
  • Rush University Medical Center โ€” Chicago, Illinois
  • University of Illinois Hospital & Health Sciences System โ€” Chicago, Illinois
  • Advocate Aurora Health โ€” Park Ridge, Illinois
  • University of Louisville โ€” Louisville, Kentucky
  • University of Maryland โ€” Baltimore, Maryland
  • Karmanos Cancer Institute โ€” Detroit, Michigan
  • University of Minnesota โ€” Minneapolis, Minnesota
  • University of Nebraska Medical Center โ€” Omaha, Nebraska
  • MD Anderson Cooper โ€” Camden, New Jersey
  • New York University Langone Medical Center โ€” New York, New York
  • Memorial Sloan Kettering Cancer Center โ€” New York, New York
  • University of North Carolina โ€” Chapel Hill, North Carolina
  • Novant Health - Winston-Salem โ€” Winston-Salem, North Carolina
  • Sanford Roger Maris Cancer Center โ€” Fargo, North Dakota
  • University of Cincinnati Medical Center โ€” Cincinnati, Ohio
  • Ohio State University Comprehensive Cancer Center โ€” Columbus, Ohio
  • Oregon Health and Science University โ€” Portland, Oregon
  • Allegheny General Hospital โ€” Natrona Heights, Pennsylvania
  • Sanford Cancer Center โ€” Sioux Falls, South Dakota
  • Avera Medical Group Cancer Institute โ€” Sioux Falls, South Dakota
  • University of Tennessee Medical Center โ€” Knoxville, Tennessee
  • Baptist Cancer Center โ€” Memphis, Tennessee

๐Ÿ“ž Contact the Study Coordinator

Phone: (844) 845-4682

Email: Clinical.Inquiries@iovance.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—