A Study of Galcanezumab (LY2951742) in Participants 12 to 17 Years of Age With Chronic Migraine (NCT04616326)
A Randomized, Double-Blind, Placebo-Controlled Study of Galcanezumab in Adolescent Patients 12 to 17 Years of Age With Chronic Migraine - the REBUILD-2 Study
🩺 Plain-English Summary (8th-Grade Level)
The main purpose of this study is to evaluate the efficacy and safety of galcanezumab for the preventive treatment of chronic migraine in participants 12 to 17 years of age. The primary objective is to demonstrate the superiority of galcanezumab versus placebo in the reduction of monthly migraine headache days across the 3-month double-blind treatment period.
Who can join: Review the eligibility criteria below.
Location: Rehabilitation & Neurological Services — Huntsville, Alabama
Age range: 12 Years to 17 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (88 Sites)
Showing the first 25 of 88 sites.
- Rehabilitation & Neurological Services — Huntsville, Alabama
- 21st Century Neurology, a Division of Xenoscience, Inc. — Phoenix, Arizona
- Phoenix Children's Hospital — Phoenix, Arizona
- Center for Neurosciences — Tucson, Arizona
- Miller Children's & Women's Hospital Long Beach — Long Beach, California
- Children's Hospital Colorado — Aurora, Colorado
- Northwest Florida Clinical Research Group — Gulf Breeze, Florida
- Clinical Neuroscience Solutions, Inc. dba CNS Healthcare — Jacksonville, Florida
- Vitaly Clinical Research — Miami, Florida
- EMDA Clinical Research — Miami, Florida
- Bio-Medical Research LLC — Miami, Florida
- Allied Biomedical Research Institute — Miami, Florida
- Ezy Medical Research — Miami Lakes, Florida
- Wellness Clinical Research — Miami Lakes, Florida
- Avanza Medical Research Center — Pensacola, Florida
- D&H Tamarac Research Center — Tamarac, Florida
- Infinity Life Research Group — Tamarac, Florida
- USF Health — Tampa, Florida
- Palm Beach Research Center — West Palm Beach, Florida
- Medical Research Partners — Ammon, Idaho
- Northwest Clinical Trials — Boise, Idaho
- St. Alexius Medical Center — Hoffman Estates, Illinois
- Ascension Via Christi Research — Wichita, Kansas
- University of Kentucky Chandler Medical Center — Lexington, Kentucky
- Pharmasite Research, Inc. — Baltimore, Maryland
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Chronic Migraine
- A Study to Evaluate the Effectiveness and Safety of Dysport® for the Prevention of Chronic Migraine in Adults — Birmingham, Alabama
- Effects of Online Mindfulness Therapy on Pain and Stress in Adults With Chronic Migraine and Adverse Childhood Experiences — Bucaramanga, Santander Department
- Cannabis for Chronic Headaches in Adolescents: the CAN-CHA Trial — Vancouver, British Columbia
- BOTOX® vs. XEOMIN® for Chronic Migraine — Jacksonville, North Carolina
- Cannabis for the Prophylactic Treatment of Migraine — Calgary, Alberta
Explore by condition: All Chronic Migraine clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.