๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-04-07

Post-op T-DM1 in HER-2+ Salivary Gland Carcinomas (NCT04620187)

A Phase II Study of Adjuvant Ado-trastuzumab Emtansine (T-DM1) in HER2-positive Salivary Gland Carcinomas

๐ŸŸข Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Dana-Farber Cancer Institute

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This research is being done to see how safe and effective the use of the study drug Ado-trastuzumab (T) emtansine (DM1), T-DM1, and standard of care chemoradiation are when used together in treating HER2-positive salivary gland cancer. It will also examine the effectiveness of study drug Ado-trastuzumab (T) emtansine (DM1) on cancer recurrence.

Who can join: Review the eligibility criteria below.

Location: Winship Cancer Institute, Emory University โ€” Atlanta, Georgia

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (13 Sites)

  • Winship Cancer Institute, Emory University โ€” Atlanta, Georgia
  • University of Chicago โ€” Chicago, Illinois
  • Brigham and Women's Hospital โ€” Boston, Massachusetts
  • Dana Farber Cancer Institute โ€” Boston, Massachusetts
  • Memorial Sloan Kettering Basking Ridge โ€” Basking Ridge, New Jersey
  • Memorial Sloan Kettering Monmouth โ€” Middletown, New Jersey
  • Memorial Sloan Kettering Bergen โ€” Montvale, New Jersey
  • Memorial Sloan Kettering Commack โ€” Commack, New York
  • Memorial Sloan Kettering Westchester โ€” Harrison, New York
  • David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center โ€” New York, New York
  • Memorial Sloan Kettering Cancer Center โ€” New York, New York
  • Memorial Sloan Kettering Nassau โ€” Uniondale, New York
  • University of Washington Medical Center โ€” Seattle, Washington

๐Ÿ“ž Contact the Study Coordinator

Phone: (617) 632-3090

Email: glenn_hanna@dfci.harvard.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—