🏛️ Verified NIH Record • Updated 2025-11-21

Active Surveillance and Surgery Outcomes in Low Risk Papillary Thyroid Cancer (NCT04624477)

Active Surveillance or Surgery for Primary Management of Very Low Risk Papillary Thyroid Cancer: How Often Are the Long-term Disease Management Goals Achieved?

🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: University Health Network, Toronto

🩺 Plain-English Summary (8th-Grade Level)

This is a prospective, observational, multi-center study examining the long-term outcomes of patients with small, low risk papillary thyroid cancer who offered the choice of active surveillance (close follow-up to monitor for potential disease progression) or immediate surgery.

Who can join: Review the eligibility criteria below.

Location: University of Calgary, Cumming School of Medicine — Calgary, Alberta

Age range: 18 Years

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (8 Sites)

  • University of Calgary, Cumming School of Medicine — Calgary, Alberta
  • University of British Columbia — Vancouver, British Columbia
  • Nova Scotia Health — Halifax, Nova Scotia
  • St. Joseph's Healthcare — Hamilton, Ontario
  • Lawson Health Research Institute — London, Ontario
  • University Health Network — Toronto, Ontario
  • Division chirurgie ORL et cervico-faciale — Montreal, Quebec
  • CHU de Québec - Université Laval — Québec, Quebec

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗