🏛️ Verified NIH Record • Updated 2026-03-04
Effect of Weight Loss on Urinary Oxalate Excretion in Obese Calcium Oxalate Kidney Stone Formers (NCT04633811)
Effect of Weight Loss on Urinary Oxalate Excretion in Obese Calcium Oxalate Kidney Stone
🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol Sponsor: University of Alabama at Birmingham
🩺 Plain-English Summary (8th-Grade Level)
This protocol seeks to determine if weight reduction with the Optifast VLCD program leads to reduced contribution of endogenous oxalate synthesis and dietary oxalate absorption to the urinary oxalate pool in obese calcium oxalate stone formers.
Who can join: Review the eligibility criteria below.
Location: University of Alabama at Birmingham — Birmingham, Alabama
Age range: 19 Years to 65 Years
🧪 Interventions in This Study
- Low Oxalate Diet before Weight Loss (DIETARY_SUPPLEMENT)
- Oral load of oxalate and sucralose before Weight Loss (DIETARY_SUPPLEMENT)
- Optifast VLCD Program (DIETARY_SUPPLEMENT)
- Optifast VLCD Transition Phase (DIETARY_SUPPLEMENT)
- Low Oxalate Diet after Weight Loss (DIETARY_SUPPLEMENT)
- Oral load of oxalate and sucralose after Weight Loss (DIETARY_SUPPLEMENT)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- University of Alabama at Birmingham — Birmingham, Alabama
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- Influence of Obesity on Oxalate Metabolism and Handling in Calcium Oxalate Stone Formers — Birmingham, Alabama
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.