🏛️ Verified NIH Record • Updated 2026-03-24

177 LuPSMA-617 vs Docetaxel in Metastatic Castration Resistant and PSMA-Positive Prostate Cancer (NCT04663997)

A Randomized Phase II Study of 177 LuPSMA-617 vs Docetaxel in Patients With Metastatic Castration-Resistant Prostate Cancer and PSMA-Positive Disease

🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Canadian Cancer Trials Group

🩺 Plain-English Summary (8th-Grade Level)

177Lu PSMA 617 is a new type of therapy which is designed to deliver high doses of radiation directly to prostate cancer sites in the body. The purpose of this study is to find out whether 177Lu PSMA 617can slow the growth of prostate cancer compared to standard chemotherapy treatment

Who can join: Review the eligibility criteria below.

Location: Tom Baker Cancer Centre — Calgary, Alberta

Age range: 18 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (10 Sites)

  • Tom Baker Cancer Centre — Calgary, Alberta
  • Cross Cancer Institute — Edmonton, Alberta
  • BCCA - Vancouver Cancer Centre — Vancouver, British Columbia
  • London Regional Cancer Program — London, Ontario
  • Odette Cancer Centre — Toronto, Ontario
  • University Health Network — Toronto, Ontario
  • CHUM-Centre Hospitalier de l'Universite de Montreal — Montreal, Quebec
  • The Jewish General Hospital — Montreal, Quebec
  • Hotel-Dieu de Quebec — Québec, Quebec
  • CIUSSS de l'Estrie - Centre hospitalier — Sherbrooke, Quebec

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Prostate Cancer clinical trials

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗