๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-03-27

Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors (NCT04665206)

Phase I/II, Multi-Center, Open-Label Study of VT3989, Alone or in Combination, in Patients With Locally Advanced or Metastatic Solid Tumors

๐ŸŸข Recruiting Phase1 / Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Vivace Therapeutics, Inc

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is an open-label, dose escalation and expansion study to evaluate the safety, tolerability, PK, and biological activity of VT3989 administered, alone or in combination, once daily in patients with mesothelioma and/or metastatic solid tumors that are resistant to standard therapy or for which no effective standard therapy is available.

Who can join: Review the eligibility criteria below.

Location: UCSF Helen Diller Family Comprehensive Cancer Center โ€” San Francisco, California

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (12 Sites)

  • UCSF Helen Diller Family Comprehensive Cancer Center โ€” San Francisco, California
  • University of Chicago Medical Center โ€” Chicago, Illinois
  • Massachusetts General Hospital โ€” Boston, Massachusetts
  • Dana-Farber Cancer Institute โ€” Boston, Massachusetts
  • M Health Fairview University of Minnesota Medical Center โ€” Minneapolis, Minnesota
  • Memorial Sloan Kettering Cancer Center โ€” New York, New York
  • MD Anderson Cancer Center โ€” Houston, Texas
  • NEXT Oncology โ€” San Antonio, Texas
  • Virginia Cancer Specialists, PC โ€” Arlington, Virginia
  • Monash Health โ€” Clayton, Victoria
  • Peter MacCullum Cancer Centre โ€” Melbourne, Victoria
  • Linear Clinical Research โ€” Nedlands, Western Australia

๐Ÿ“ž Contact the Study Coordinator

Phone: (650) 627-7437

Email: hfritz@inclin.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—