Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors (NCT04665206)
Phase I/II, Multi-Center, Open-Label Study of VT3989, Alone or in Combination, in Patients With Locally Advanced or Metastatic Solid Tumors
๐ฉบ Plain-English Summary (8th-Grade Level)
This is an open-label, dose escalation and expansion study to evaluate the safety, tolerability, PK, and biological activity of VT3989 administered, alone or in combination, once daily in patients with mesothelioma and/or metastatic solid tumors that are resistant to standard therapy or for which no effective standard therapy is available.
Who can join: Review the eligibility criteria below.
Location: UCSF Helen Diller Family Comprehensive Cancer Center โ San Francisco, California
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (12 Sites)
- UCSF Helen Diller Family Comprehensive Cancer Center โ San Francisco, California
- University of Chicago Medical Center โ Chicago, Illinois
- Massachusetts General Hospital โ Boston, Massachusetts
- Dana-Farber Cancer Institute โ Boston, Massachusetts
- M Health Fairview University of Minnesota Medical Center โ Minneapolis, Minnesota
- Memorial Sloan Kettering Cancer Center โ New York, New York
- MD Anderson Cancer Center โ Houston, Texas
- NEXT Oncology โ San Antonio, Texas
- Virginia Cancer Specialists, PC โ Arlington, Virginia
- Monash Health โ Clayton, Victoria
- Peter MacCullum Cancer Centre โ Melbourne, Victoria
- Linear Clinical Research โ Nedlands, Western Australia
๐ Contact the Study Coordinator
Phone: (650) 627-7437
Email: hfritz@inclin.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Solid Tumor, Adult
- A Study of HST-1011 Given as Monotherapy and in Combination With an Anti-PD1 Antibody โ Sarasota, Florida
- First-in-Human Study of ICT01 in Patients With Advanced Cancer โ Gilbert, Arizona
- A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors โ Los Angeles, California
- Study Assessing MTD, Safety, Tolerability, PK and Anti-tumor Effects of LNS8801alone and With Pembrolizumab โ Los Angeles, California
- A Rollover Study for Subjects Who Completed Participation in IMSA101-101 Trial โ Scottsdale, Arizona
- A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression โ Gilbert, Arizona
Explore by condition: All Solid Tumor, Adult clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.