A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors (NCT04673942)
An Adapted Phase 2a/2b, Study to Evaluate the Safety, Tolerability, and Efficacy of AdAPT-001 in Subjects With Refractory Solid Tumors
๐ฉบ Plain-English Summary (8th-Grade Level)
AdAPT-001 is an oncolytic virus that is injected directly into the tumor or via intraarterial administration. The purpose of this study is to find out if AdAPT-001 is safe and tolerable. The next step is to find out if AdAPT-001 if efficacious with or without a checkpoint inhibitor.
Who can join: Review the eligibility criteria below.
Location: City of Hope โ Duarte, California
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (6 Sites)
- City of Hope โ Duarte, California
- California Cancer Associates for Research and Excellence, cCARE โ San Marcos, California
- Providence Saint John's Health Center โ Santa Monica, California
- Cleveland Clinic โ Cleveland, Ohio
- Mary Crowley Cancer Research โ Dallas, Texas
- MD Anderson Cancer Center โ Houston, Texas
๐ Contact the Study Coordinator
Phone: (800) 826-4673
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- A Rollover Study for Subjects Who Completed Participation in IMSA101-101 Trial โ Scottsdale, Arizona
- A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression โ Gilbert, Arizona
Explore by condition: All Solid Tumor, Adult clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.