Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised Hosts (NCT04691622)
🩺 Plain-English Summary (8th-Grade Level)
This is a Phase I dose-escalation study to evaluate the safety of norovirus -specific T-cell (NST) therapy for chronic norovirus infection in participants following hematopoietic stem cell transplantation (HSCT) or who are immunocompromised due to PID and have not undergone HSCT, or Solid Organ Transplant (SOT) recipients.
Who can join: Review the eligibility criteria below.
Location: Children's National Hospital — Washington D.C., District of Columbia
Age range: 3 Months to 80 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (3 Sites)
- Children's National Hospital — Washington D.C., District of Columbia
- Johns Hopkins University — Baltimore, Maryland
- National Institutes of Health (NIH) — Bethesda, Maryland
📞 Contact the Study Coordinator
Phone: (202) 476-5843
Email: MKeller@childrensnational.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Viral Infection
- Adoptive Cord Blood Immunotherapy for EBV, CMV, BKV and Adenovirus Reactivation/Infection or Prophylaxis — Washington D.C., District of Columbia
- Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs) — San Francisco, California
- Third Party Viral Specific T-cells (VSTs) — Akron, Ohio
- School Inner City Air Study — Boston, Massachusetts
- TETRAVI Multivirus CTL for Treatment of EBV, CMV, Adenovirus, and BK Infections Post Allogeneic SCT. — Houston, Texas
Explore by condition: All Viral Infection clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.