Trifecta-Heart cfDNA-MMDx Study (NCT04707872)
Trifecta-Heart cfDNA-MMDX Study: Comparing the DD-cfDNA Test to MMDx Microarray Test and Central HLA Antibody Test
🩺 Plain-English Summary (8th-Grade Level)
Demonstrate the relationship between DD-cfDNA levels and HLA antibodies in blood transplant recipient and the Molecular Microscope® (MMDx) Diagnostic System results in indication and protocol biopsies from heart transplants.
Who can join: Review the eligibility criteria below.
Location: Baptist Health Institute for Research and Innovation — Little Rock, Arkansas
🧪 Interventions in This Study
- MMDx diagnostic test (DIAGNOSTIC_TEST)
- Prospera (DIAGNOSTIC_TEST)
- HLA antibody (DIAGNOSTIC_TEST)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (12 Sites)
- Baptist Health Institute for Research and Innovation — Little Rock, Arkansas
- Tampa General Hospital, 409 Bayshore Blvd. — Tampa, Florida
- Columbia University Medical Center, Columbia Interventional Cardiovascular Care — West New York, New Jersey
- Montefiore Medical Center, 3319 Rochambeau Avenue, 2nd FL — The Bronx, New York
- Annette C. and Harold C. Simmons Transplant Institute, BaylorScott&White Research Institute — Dallas, Texas
- Cardiovascular Medicine, University of Utah Health — Salt Lake City, Utah
- Cardiac Transplantation Laboratory, The Victor Chang Cardiac Research Institute — Darlinghurst,
- Division of Cardiology, University of Alberta — Edmonton, Alberta
- Institute for Clinical and Experimental Medicine - IKEM Videnska 1958/9 — Prague,
- Heart Failure and Heart Transplant Unit, University of Bologna — Bologna,
- Silesian Center for Heart Diseases (Ś!ąskie Centrum Chorób Serca w Zabrzu — Zabrze,
- Advanced Heart Failure Transplant Unit — A Coruña,
📞 Contact the Study Coordinator
Phone: (780) 782-9463
Email: konrad@ualberta.ca
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Heart Transplant Rejection
- Surveillance HeartCare® Outcomes Registry — Phoenix, Arizona
- Prospera Test Evaluation in Cardiac Transplant (ProTECT) — San Carlos, California
- Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients — Coral Gables, Florida
Explore by condition: All Heart Transplant Rejection clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.