Lung Macrophage Populations and Functions in Chronic Obstructive Pulmonary Disease (COPD)-Susceptible Smokers (NCT04722835)
๐ฉบ Plain-English Summary (8th-Grade Level)
Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous disease that affects only a fraction of those who smoke tobacco. The origin of this variability in susceptibility to develop COPD is unclear, but understanding its underlying biology has important implications for our ability to design suitable preventative and therapeutic strategies for its management. This Department of Defense (DOD) discovery research proposes to develop methodologies and generate preliminary data needed to lay the foundation for a large study that would investigate the underlying biological susceptibility of those who smoke tobacco to develop COPD.
Who can join: Review the eligibility criteria below.
Location: Zuckerberg San Francisco General Hospital and Trauma Center โ San Francisco, California
Age range: 40 Years to 75 Years
๐งช Interventions in This Study
- Bronchoscopy with Bronchoalveolar Lavage (BAL) (PROCEDURE)
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (3 Sites)
- Zuckerberg San Francisco General Hospital and Trauma Center โ San Francisco, California
- San Francisco VA Medical Center โ San Francisco, California
- University of California, San Francisco โ San Francisco, California
๐ Contact the Study Coordinator
Phone: (415) 221-4810
Email: yorusaliem.abrham@ucsf.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- A Study to Evaluate Solrikitug in Participants With COPD (ZION) โ Birmingham, Alabama
- RELVAR Effects on Parasternal Muscle Activity, Diaphragm, and Ventilation in Severe COPD โ Calgary, Alberta
- Evaluation of the Safety and Efficacy of TLD in Patients with COPD โ Birmingham, Alabama
Explore by condition: All Copd clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.