๐๏ธ Verified NIH Record โข Updated 2026-04-14
Study to Assess the Safety, Tolerability, and Efficacy of IDX-1197 in Combination With XELOX or Irinotecan in Patients With Advanced Gastric Cancer (NCT04725994)
An Open-Label, International, Multicenter, Phase 1b/2a Study to Assess the Safety, Tolerability, and Efficacy of IDX-1197 in Combination With XELOX (Capecitabine and Oxaliplatin) or Irinotecan in Patients With Advanced Gastric Cancer
๐ต Active, Not Recruiting Phase1 / Phase2 ๐ Investigational Drug / Biologic Sponsor: Idience Co., Ltd.
๐ฉบ Plain-English Summary (8th-Grade Level)
This is an open-label, Phase 1b/2a study to evaluate the safety and tolerability of IDX-1197 and determine the MTD and RP2D in combination with XELOX or irinotecan in patients with advanced gastric cancer.
Who can join: Review the eligibility criteria below.
Location: USC Norris Comp. Cancer Ctr Hospital โ Los Angeles, California
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (17 Sites)
- USC Norris Comp. Cancer Ctr Hospital โ Los Angeles, California
- Hematology Oncology Clinic Baton Rouge / Sarah Cannon โ Baton Rouge, Louisiana
- Beth Israel Deaconess Medical Center โ Boston, Massachusetts
- Dana Farber Cancer Institute โ Boston, Massachusetts
- Astera Cancer Care โ East Brunswick, New Jersey
- Beijing Cancer Hospital โ Beijing,
- The Sixth Affiliated Hospital of Sun Yat-Sen University โ Guangzhou,
- Shanghai East Hospital โ Shanghai,
- Jeonbuk National University Hospital โ Jeonju, Jeollabuk-do
- Dong-A University Hospital โ Busan,
- Seoul National University Bundang Hospital โ Seongnam,
- Korea University Anam Hospital โ Seoul,
- Korea University Guro Hospital โ Seoul,
- Asan Medical Center โ Seoul,
- Samsung Medical Center โ Seoul,
- Seoul National University Hospital โ Seoul,
- Severance Hospital - Yonsei Cancer Center โ Seoul,
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03) โ Baltimore, Maryland
- Nivolumab +/- Relatlimab Prior to Chemoradiation With II/III Gastro/Esophageal Cancer โ Baltimore, Maryland
- Study for AZD4360 in Participants With Advanced Solid Tumours โ Santa Monica, California
- Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma โ Tampa, Florida
Explore by condition: All Gastric Cancer clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.