๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-03-25

Dynamic in Vivo PET Imaging and ex Vivo Biopsies From Skeletal Muscle and Adipose Tissue to Investigate the Effects of Exercise on Insulin Resistance and Mitochondrial Energetics in Type 2 Diabetes (NCT04754581)

๐Ÿ”ต Active, Not Recruiting Observational / Diagnostic ๐Ÿฉบ Clinical Procedure Protocol Sponsor: AdventHealth Translational Research Institute

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The overall aim of this pilot study is to investigate the effects of exercise training on skeletal muscle and adipose tissue insulin resistance in subjects with Type 2 Diabetes (T2D).

Who can join: Review the eligibility criteria below.

Location: AdventHealth Translational Research Institute โ€” Orlando, Florida

Age range: 30 Years to 65 Years

๐Ÿงช Interventions in This Study

  • Maximal ATP Production (ATPmax) (OTHER)
  • Exercise Testing (VO2max) (OTHER)
  • Muscle Biopsy (PROCEDURE)
  • Adipose Tissue Biopsy (PROCEDURE)
  • Hyperinsulinemic euglycemic clamp (OTHER)
  • PET imaging (OTHER)

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (1 Sites)

  • AdventHealth Translational Research Institute โ€” Orlando, Florida

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Type 2 Diabetes clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—