🏛️ Verified NIH Record • Updated 2025-11-04
Safety and Tolerability of Abelacimab (MAA868) vs. Rivaroxaban in Patients With Atrial Fibrillation (NCT04755283)
A Multicenter, RandomiZed, Active-ControLled Study to Evaluate the Safety and Tolerability of Two Blinded Doses of Abelacimab (MAA868) Compared With Open-Label Rivaroxaban in Patients With Atrial Fibrillation (AZALEA)
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Anthos Therapeutics, Inc.
🩺 Plain-English Summary (8th-Grade Level)
The purpose of the ANT-006 study is to evaluate the bleeding profile of abelacimab relative to rivaroxaban in patients with atrial fibrillation (AF) at moderate-to-high risk of stroke.
Who can join: Review the eligibility criteria below.
Location: Anthos Investigative Site — Huntsville, Alabama
Age range: 55 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (92 Sites)
Showing the first 25 of 92 sites.
- Anthos Investigative Site — Huntsville, Alabama
- Anthos Investigative Site — Mobile, Alabama
- Anthos Investigative Site — Stamford, Connecticut
- Anthos Investigative Site — Clearwater, Florida
- Anthos Investigative Site — Daytona Beach, Florida
- Anthos Investigative Site — Largo, Florida
- Anthos Investigative Site — Safety Harbor, Florida
- Anthos Investigative Site — Saint Augustine, Florida
- Anthos Investigative Site — Johns Creek, Georgia
- Anthos Investigative Site — Owensboro, Kentucky
- Anthos Investigative Site — Baltimore, Maryland
- Anthos Investigative Site — Salisbury, Maryland
- Anthos Investigative Site — Framingham, Massachusetts
- Anthos Investigative Site — Haverhill, Massachusetts
- Anthos Investigative Site — Lansing, Michigan
- Anthos Investigative Site — Sewell, New Jersey
- Anthos Investigative Site — Poughkeepsie, New York
- Anthos Investigative Site — Southampton, New York
- Anthos Investigative Site — Lenoir, North Carolina
- Anthos Investigative Site — Fargo, North Dakota
- Anthos Investigative Site — Oklahoma City, Oklahoma
- Anthos Investigative Site — Camp Hill, Pennsylvania
- Anthos Investigative Site — Kingsport, Tennessee
- Anthos Investigative Site — Kingwood, Texas
- Anthos Investigative Site — Odessa, Texas
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Atrial Fibrillation (AF)
- Detection and Classification of Cardiac Rhythm and Atrial Fibrillation Using a Finger-worn Ring — La Jolla, California
- Phase-Aligned Atrial Fibrillation Mapping — Cleveland, Ohio
- Left Atrial Pressure-Guided Heart Failure Optimization During Atrial Fibrillation Ablation (LAP AF-HF) — Milwaukee, Wisconsin
- AtriCure CryoICE Lesions for Persistent and Long-standing Persistent Atrial Fibrillation Treatment — Los Angeles, California
- P-wave Duration and Local Potential as Predictors of AF Recurrence Following Pulmonary Vein Isolation — Paramus, New Jersey
Explore by condition: All Atrial Fibrillation (AF) clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.