๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-10

A Study of BGB-11417 in Participants With Myeloid Malignancies (NCT04771130)

A Phase 1b/2, Open-Label, Dose Finding, and Expansion Study of the Bcl-2 Inhibitor BGB-11417 in Patients With Myeloid Malignancies

๐ŸŸข Recruiting Phase1 / Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: BeOne Medicines

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The study will determine the safety, tolerability, recommended Phase 2 dose (RP2D) and preliminary efficacy of BGB-11417 as monotherapy and in combination with azacitidine in participants with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS)or MDS/myeloproliferative neoplasm (MPN) .

Who can join: Review the eligibility criteria below.

Location: City of Hope National Medical Center โ€” Duarte, California

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (46 Sites)

Showing the first 25 of 46 sites.

  • City of Hope National Medical Center โ€” Duarte, California
  • Tampa General Hospital โ€” Tampa, Florida
  • Upmc Hillman Cancer Center(Univ of Pittsburgh) โ€” Pittsburgh, Pennsylvania
  • Md Anderson Cancer Center โ€” Houston, Texas
  • Medical College of Wisconsin โ€” Milwaukee, Wisconsin
  • Concord Repatriation General Hospital โ€” Concord, New South Wales
  • St George Hospital โ€” Kogarah, New South Wales
  • Orange Health Hospital โ€” Orange, New South Wales
  • Gold Coast University Hospital โ€” Southport, Queensland
  • Monash Health โ€” Clayton, Victoria
  • St Vincents Hospital Melbourne โ€” Fitzroy, Victoria
  • Austin Health โ€” Heidelberg, Victoria
  • The Alfred Hospital โ€” Melbourne, Victoria
  • Fiona Stanley Hospital โ€” Murdoch, Western Australia
  • Linear Clinical Research โ€” Nedlands, Western Australia
  • One Clinical Research โ€” Nedlands, Western Australia
  • Peking University Peoples Hospital โ€” Beijing, Beijing Municipality
  • The First Hospital of Lanzhou University โ€” Lanzhou, Gansu
  • Guangdong Provincial Peoples Hospital โ€” Guangzhou, Guangdong
  • Nanfang Hospital, Southern Medical University โ€” Guangzhou, Guangdong
  • The Second Peoples Hospital of Shenzhen โ€” Shenzhen, Guangdong
  • Henan Cancer Hospital โ€” Zhengzhou, Henan
  • Union Hospital of Tongji Medical College, Huazhong University of Science and Technology โ€” Wuhan, Hubei
  • The First Affiliated Hospital of Soochow University โ€” Suzhou, Jiangsu
  • The First Affiliated Hospital of Nanchang University Branch Donghu โ€” Nanchang, Jiangxi

๐Ÿ“ž Contact the Study Coordinator

Phone: (877) 828-5568

Email: clinicaltrials@beonemed.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—