A Study of BGB-11417 in Participants With Myeloid Malignancies (NCT04771130)
A Phase 1b/2, Open-Label, Dose Finding, and Expansion Study of the Bcl-2 Inhibitor BGB-11417 in Patients With Myeloid Malignancies
๐ฉบ Plain-English Summary (8th-Grade Level)
The study will determine the safety, tolerability, recommended Phase 2 dose (RP2D) and preliminary efficacy of BGB-11417 as monotherapy and in combination with azacitidine in participants with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS)or MDS/myeloproliferative neoplasm (MPN) .
Who can join: Review the eligibility criteria below.
Location: City of Hope National Medical Center โ Duarte, California
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (46 Sites)
Showing the first 25 of 46 sites.
- City of Hope National Medical Center โ Duarte, California
- Tampa General Hospital โ Tampa, Florida
- Upmc Hillman Cancer Center(Univ of Pittsburgh) โ Pittsburgh, Pennsylvania
- Md Anderson Cancer Center โ Houston, Texas
- Medical College of Wisconsin โ Milwaukee, Wisconsin
- Concord Repatriation General Hospital โ Concord, New South Wales
- St George Hospital โ Kogarah, New South Wales
- Orange Health Hospital โ Orange, New South Wales
- Gold Coast University Hospital โ Southport, Queensland
- Monash Health โ Clayton, Victoria
- St Vincents Hospital Melbourne โ Fitzroy, Victoria
- Austin Health โ Heidelberg, Victoria
- The Alfred Hospital โ Melbourne, Victoria
- Fiona Stanley Hospital โ Murdoch, Western Australia
- Linear Clinical Research โ Nedlands, Western Australia
- One Clinical Research โ Nedlands, Western Australia
- Peking University Peoples Hospital โ Beijing, Beijing Municipality
- The First Hospital of Lanzhou University โ Lanzhou, Gansu
- Guangdong Provincial Peoples Hospital โ Guangzhou, Guangdong
- Nanfang Hospital, Southern Medical University โ Guangzhou, Guangdong
- The Second Peoples Hospital of Shenzhen โ Shenzhen, Guangdong
- Henan Cancer Hospital โ Zhengzhou, Henan
- Union Hospital of Tongji Medical College, Huazhong University of Science and Technology โ Wuhan, Hubei
- The First Affiliated Hospital of Soochow University โ Suzhou, Jiangsu
- The First Affiliated Hospital of Nanchang University Branch Donghu โ Nanchang, Jiangxi
๐ Contact the Study Coordinator
Phone: (877) 828-5568
Email: clinicaltrials@beonemed.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.