๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-03-06

ARX788 in HER2-positive, Metastatic Breast Cancer Subjects (ACE-Breast-03) (NCT04829604)

A Global, Phase 2 Study of ARX788 in HER2-positive Metastatic Breast Cancer Patients Who Were Previously Treated With T-DXd

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Ambrx, Inc.

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

A Global, Phase 2 Study of ARX788 in HER2-positive Metastatic Breast Cancer Patients who were previously treated with T-DXd

Who can join: Review the eligibility criteria below.

Location: Research Site โ€” Los Angeles, California

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (33 Sites)

Showing the first 25 of 33 sites.

  • Research Site โ€” Los Angeles, California
  • Research Site โ€” Newport Beach, California
  • Research Site โ€” San Francisco, California
  • Research Site โ€” Whittier, California
  • Research Site โ€” Atlanta, Georgia
  • Research Site โ€” Chicago, Illinois
  • Research Site โ€” Louisville, Kentucky
  • Research Site โ€” Silver Spring, Maryland
  • Research Site โ€” Boston, Massachusetts
  • Research Site โ€” St Louis, Missouri
  • Research Site โ€” Omaha, Nebraska
  • Research Site โ€” Las Vegas, Nevada
  • Research Site โ€” Camden, New Jersey
  • Research Site โ€” New Hyde Park, New York
  • Research Site โ€” New York, New York
  • Research Site โ€” Shirley, New York
  • Research Site โ€” The Bronx, New York
  • Research Site โ€” Portland, Oregon
  • Research Site โ€” Tigard, Oregon
  • Research Site โ€” Philadelphia, Pennsylvania
  • Research Site โ€” Dallas, Texas
  • Research Site โ€” Houston, Texas
  • Research Site โ€” San Antonio, Texas
  • Research Site โ€” Norfolk, Virginia
  • Research Site โ€” Tacoma, Washington

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—