🏛️ Verified NIH Record • Updated 2026-07-01
A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 ) (NCT04849728)
A Randomised, Double-blind, Placebo-controlled, Multicentre, Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With Non-cirrhotic Non-alcoholic Steatohepatitis (NASH) and Fibrosis Stages F2 and F3
🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: Inventiva Pharma
🩺 Plain-English Summary (8th-Grade Level)
This Phase 3 study is conducted to evaluate lanifibranor in adults with NASH and liver fibrosis histological stage F2 or F3
Who can join: Review the eligibility criteria below.
Location: Objective Health - Birmingham Gastroenterology Associates — Birmingham, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (459 Sites)
Showing the first 25 of 459 sites.
- Objective Health - Birmingham Gastroenterology Associates — Birmingham, Alabama
- Digestive Health Specialist of the Southeast — Dothan, Alabama
- North Alabama GI Research Center llc — Madison, Alabama
- The Institute For Liver Health - Chandler — Chandler, Arizona
- Arizona Liver Health - Peoria — Peoria, Arizona
- Dignity Health - St. Joseph's Hospital and Medical Center — Phoenix, Arizona
- Saint Joseph's Hospital and Medical Center — Phoenix, Arizona
- Adobe Gastroenterology — Tucson, Arizona
- Arizona Liver Health — Tucson, Arizona
- ARcare Center for Clinical Research - Conway — Conway, Arkansas
- ARcare Center for Clinical Research — Little Rock, Arkansas
- Arkansas Diagnostic Center — Little Rock, Arkansas
- Arkansas Gastroenterology — North Little Rock, Arkansas
- Summit - Arkansas Gastroenterology — North Little Rock, Arkansas
- Fomatmedicalresearch — Camarillo, California
- GW Research — Chula Vista, California
- Velocity Clinical Research, Chula Vista — Chula Vista, California
- TriWest Research Associates — El Cajon, California
- Cure Clinical Research, LLC — Fountain Valley, California
- SC Clinical Research — Garden Grove, California
- Velocity Clinical Research - Gardena — Gardena, California
- National Research Institute - Santa Ana — Huntington Park, California
- The Clinical Trials Network - Gastro Care Institute — Lancaster, California
- National Research Institute - Westlake — Los Angeles, California
- National Research Institute - Panorama City — Panorama City, California
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in NASH - Nonalcoholic Steatohepatitis
- Statins for the Treatment of NASH — Rochester, Minnesota
- Estrogen Administration for the Treatment of NASH in Postmenopausal Women — Boston, Massachusetts
- A Phase 3 Study to Evaluate the Efficacy and Safety of MGL-3196 (Resmetirom) in Patients With NASH and Fibrosis — Birmingham, Alabama
- Novel MRE Technique to Assess a Risk Factor for Liver Cancer — Stanford, California
- Hepatic Energy Fluxes in NASH and NAS Patients — Minneapolis, Minnesota
Explore by condition: All NASH - Nonalcoholic Steatohepatitis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.