Radiation Therapy Boost Before Surgery for the Treatment of Non-metastatic Breast Cancer (NCT04871516)
A Single Center Phase II Prospective Clinical Trial to Assess the Feasibility of Preoperative Radiation Boost in Breast Cancer Patients
🩺 Plain-English Summary (8th-Grade Level)
This phase II trial investigates the safety of delivering a part (boost) of radiation treatment before breast surgery in treating patients with breast cancer that has not spread to other places in the body (non-metastatic). Radiation therapy uses high energy photons/electrons to kill tumor cells and shrink tumors. Delivering a boost radiation treatment before surgery when doctors can still visualize the tumor on imaging may help to better target the tumor and decrease the volume of normal irradiated tissue. By so doing, doctors may achieve better cosmetic outcomes and possibly better tumor control.
Who can join: Review the eligibility criteria below.
Location: Clara Maass Medical Center — Belleville, New Jersey
Age range: 18 Years
🧪 Interventions in This Study
- Quality-of-Life Assessment (OTHER)
- Questionnaire Administration (OTHER)
- Radiation Boost (RADIATION)
- Therapeutic Surgical Procedure (PROCEDURE)
- Whole Breast Irradiation (RADIATION)
- Breast MRI (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (11 Sites)
- Clara Maass Medical Center — Belleville, New Jersey
- RWJBarnabas Health-Trinitas Hospital and Comprehensive Care — Elizabeth, New Jersey
- The Cancer Institute of New Jersey Hamilton — Hamilton, New Jersey
- RWJBarnabas Health Jersey City Medical Center — Jersey City, New Jersey
- RWJBarnabas Health - Monmouth Medical Center Southern Campus — Lakewood, New Jersey
- Cooperman Barnabas Medical Center (Saint Barnabas Medical Center) — Livingston, New Jersey
- Rutgers Cancer Institute of New Jersey — New Brunswick, New Jersey
- Rutgers New Jersey Medical School — Newark, New Jersey
- RWJBarnabas Health - Newark Beth Israel Medical Center — Newark, New Jersey
- Robert Wood Johnson University Hospital Somerset — Somerville, New Jersey
- RWJBarnabas Health - Community Medical Center — Toms River, New Jersey
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Anatomic Stage 0 Breast Cancer AJCC v8
- Culturally Based Brief Expressive Writing Intervention for the Improvement of Health in Chinese Immigrant Stage 0-III Breast Cancer Survivors, Writing to Heal Study — Houston, Texas
- Evaluation of a Once Per Day Regimen of Accelerated Partial Breast Irradiation for Improved Breast Appearance in Pts w/Low Risk, Hormone Responsive Brst Ca — Duarte, California
- Hypnosedation in Relaxing Patients Undergoing Breast Cancer Surgery — Houston, Texas
- Web-Based Symptom Monitoring and Self-Management Portal (YES) for Adolescent and Young Adult Breast Cancer Survivors — Boston, Massachusetts
- Standard Verbal Counseling With or Without a Pictorial Educational Tool for the Reduction of Psychological Morbidity in Patients With Stage 0-IIIA Breast Cancer Receiving Radiation Therapy, COPE Study — Portland, Oregon
- Improving Patient-Centered Communication in Breast Cancer Through Patient and Provider Interventions — Vallejo, California
Explore by condition: All Anatomic Stage 0 Breast Cancer AJCC v8 clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.