Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout (NCT04875702)
Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout: A Randomized Controlled Trial
🩺 Plain-English Summary (8th-Grade Level)
The TRUST study is a randomized, controlled multicenter study to evaluate the management of gout by comparing two commonly used treatment strategies for gout (TTT vs TTASx) to determine the most beneficial for a patient-centered gout outcomes, as well as relevant cardiovascular-metabolic-renal endpoints.
Who can join: Review the eligibility criteria below.
Location: The University of Alabama at Birmingham — South Birmingham, Alabama
Age range: 18 Years to 90 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (7 Sites)
- The University of Alabama at Birmingham — South Birmingham, Alabama
- UCLA Health — Santa Monica, California
- Massachusetts General Hospital — Boston, Massachusetts
- Brigham and Women's Hospital (BWH) — Boston, Massachusetts
- Boston Medical Center (BMC) — Boston, Massachusetts
- NYU Langone — New York, New York
- West Virginia University (Including Mobile Clinical Trials Unit) — Morgantown, West Virginia
📞 Contact the Study Coordinator
Phone: (617) 643-2140
Email: adfernandes@mgh.harvard.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Gout
- Assessing the Role of the NLRP3 Inflammasome in Intercritical Gout — Beverly Hills, California
- Gout in the ED and Improving Research Participation — Birmingham, Alabama
- Evaluation of Efficacy and Safety of AR882 and XOI Co-administration in Uricase Treatment Failed Patients — Margate, Florida
- Dose Finding Study to Evaluate Safety and Efficacy of 3 Dosages of SAP 001. — Sacramento, California
- PK and Safety Evaluation Study of SAP-001 in Adult Subjects With Normal and Impaired Renal Function — Tampa, Florida
- Phase 3 Evaluation of Efficacy and Safety of AR882 in Gout Patients (AR882-301) — Birmingham, Alabama
Explore by condition: All Gout clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.