🏛️ Verified NIH Record • Updated 2026-04-23
ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP) (NCT04883905)
ELEVATE, a Global Observational Longitudinal Prospective Registry of Patients With Acute Hepatic Porphyria (AHP)
🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: Alnylam Pharmaceuticals
🩺 Plain-English Summary (8th-Grade Level)
This global patient registry is being conducted to characterize the natural history and real-world clinical management of patients with AHP, and to further characterize the real-world safety and effectiveness of givosiran and other approved AHP therapies.
Who can join: Review the eligibility criteria below.
Location: Clinical Trial Site — Birmingham, Alabama
Age range: 12 Years
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (30 Sites)
Showing the first 25 of 30 sites.
- Clinical Trial Site — Birmingham, Alabama
- Clinical Trial Site — Gilbert, Arizona
- Clinical Trial Site — San Francisco, California
- Clinical Trial Site — Baltimore, Maryland
- Clinical Trial Site — Boston, Massachusetts
- Clinical Trial Site — Minneapolis, Minnesota
- Clinical Trial Site — New York, New York
- Clinical Trial Site — Winston-Salem, North Carolina
- Clinical Trial Site — Oklahoma City, Oklahoma
- Clinical Trial Site — Philadelphia, Pennsylvania
- Clinical Trial Site — Galveston, Texas
- Clinical Trial Site — Salt Lake City, Utah
- Clinical Trial Site — Seattle, Washington
- Clinical Trial Site — Brussels,
- Clinical Trial Site — Leuven,
- Clinical Trial Site — Bordeaux,
- Clinical Trial Site — Paris,
- Clinical Trial Site — Toulouse,
- Clinical Trial Site — Berlin,
- Clinical Trial Site — Chemnitz,
- Clinical Trial Site — Würzburg,
- Clinical Trial Site — Milan,
- Clinical Trial Site — Modena,
- Clinical Trial Site — Madrid,
- Clinical Trial Site — Stockholm,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Acute Hepatic Porphyria clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.