ATEMPT 2.0: Adjuvant T-DM1 vs TH (NCT04893109)
A Randomized Phase II Trial of Adjuvant Trastuzumab Emtansine (T-DM1) Followed by Subcutaneous Trastuzumab Versus Paclitaxel in Combination With Subcutaneous Trastuzumab for Stage I HER2-positive Breast Cancer (ATEMPT 2.0)
๐ฉบ Plain-English Summary (8th-Grade Level)
This research study is studying how well newly diagnosed breast cancer that has tested positive for a protein called HER2 responds using one of two different combination of HER2-directed therapies as a treatment after surgery. The name of the study drugs involved are: * Trastuzumab-emtansine (T-DM1, Kadcyla) * Trastuzumab SC (Herceptin Hylecta) * Paclitaxel
Who can join: Review the eligibility criteria below.
Location: UCSF Helen Diller Family Comprehensive Cancer Center โ San Francisco, California
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (53 Sites)
Showing the first 25 of 53 sites.
- UCSF Helen Diller Family Comprehensive Cancer Center โ San Francisco, California
- Smilow Cancer Hospital Care center at Derby โ Derby, Connecticut
- Smilow Cancer Hospital Care center at Fairfield โ Fairfield, Connecticut
- Smilow Cancer Hospital Care center at Glastonbury โ Glastonbury, Connecticut
- Smilow Cancer Hospital Care center at Greenwich โ Greenwich, Connecticut
- Smilow Cancer Hospital Care center at Guilford โ Guilford, Connecticut
- Smilow Cancer Hospital Care center at St. Francis โ Hartford, Connecticut
- Smilow Cancer Hospital Care center at Long Ridge โ Long Ridge, Connecticut
- Yale Cancer Center at Yale University School of Medicine โ New Haven, Connecticut
- Smilow Cancer Hospital Care center at North Haven โ North Haven, Connecticut
- Stamford Hospital โ Stamford, Connecticut
- Smilow Cancer Hospital Care center at Torrington โ Torrington, Connecticut
- Smilow Cancer Hospital Care center at Trumbull โ Trumbull, Connecticut
- Smilow Cancer Hospital Care center at Waterbury โ Waterbury, Connecticut
- Smilow Cancer Hospital Care center at Waterford โ Waterford, Connecticut
- Miami Cancer Institute/Baptist Hospital of Miami โ Miami, Florida
- Miami Cancer Institute - Plantation (MCIP) โ Plantation, Florida
- The University of Chicago Medical Center โ Chicago, Illinois
- Indiana University Health Joe & Shelly Schwarz Cancer Center โ Carmel, Indiana
- IU Health North Hospital โ Carmel, Indiana
- Indiana University Melvin and Bren Simon Comprehensive Cancer Center โ Indianapolis, Indiana
- Indiana University Sidney and Lois Eskenazi Hospital โ Indianapolis, Indiana
- Eastern Maine Medical Center (Northern Light) โ Brewer, Maine
- New England Cancer Specialists โ Scarborough, Maine
- Beth Israel Deaconess Medical Center โ Boston, Massachusetts
๐ Contact the Study Coordinator
Phone: (617) 632-2335
Email: sara_tolaney@dfci.harvard.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.