Efficacy and Safety of Ofatumumab and Siponimod Compared to Fingolimod in Pediatric Patients With Multiple Sclerosis (NCT04926818)

🧪 Interventions in This Study

• Fingolimod (DRUG)
• Ofatumumab (DRUG)
• Siponimod (DRUG)

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (51 Sites)

Showing the first 25 of 51 sites.

• Arkansas Childrens Hosp Rsch Inst — Little Rock, Arkansas
• Childrens Hospital Los Angeles — Los Angeles, California
• Childrens National Medical Center — Washington D.C., District of Columbia
• Axiom Clinical Research of Florida — Tampa, Florida
• Childrens Hospital of Philadelphia — Philadelphia, Pennsylvania
• Medical College of Wisconsin — Milwaukee, Wisconsin
• Novartis Investigative Site — CABA,
• Novartis Investigative Site — Parkville, Victoria
• Novartis Investigative Site — Vienna,
• Novartis Investigative Site — Esneux,
• Novartis Investigative Site — Ghent,
• Novartis Investigative Site — Curitiba, Paraná
• Novartis Investigative Site — Porto Alegre, Rio Grande do Sul
• Novartis Investigative Site — São Paulo, São Paulo
• Novartis Investigative Site — Montreal, Quebec
• Novartis Investigative Site — Montreal, Quebec
• Novartis Investigative Site — Lo Barnechea, Santiago Metropolitan
• Novartis Investigative Site — Zagreb,
• Novartis Investigative Site — Tallinn,
• Novartis Investigative Site — Le Kremlin-Bicêtre,
• Novartis Investigative Site — Montpellier,
• Novartis Investigative Site — Strasbourg,
• Novartis Investigative Site — Freiburg im Breisgau, Baden-Wurttemberg
• Novartis Investigative Site — Göttingen, Lower Saxony
• Novartis Investigative Site — Bochum,

💰 Cost, Insurance & Patient Rights

• 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
• Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
• Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Multiple Sclerosis (MS)

• A Phase I Double Blind Study of Metformin Acting on Endogenous Neural Progenitor Cells in Children and Young Adults With Multiple Sclerosis — Toronto, Ontario
• Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair Therapy — San Francisco, California
• Increasing Physical Activity for Adults With Multiple Sclerosis (MS) — Seattle, Washington

Explore by condition: All Multiple Sclerosis (MS) clinical trials

💡 How to Participate

1. Check the checklist above to see if you may qualify.
2. Review the official NIH record below to find the coordinating site.
3. Ask about the visit schedule, what is covered at no cost, and any travel support.
4. Confirm with your own doctor before making a decision.