🏛️ Verified NIH Record • Updated 2025-02-13
The Hancock Jaffe Surgical Antireflux Venous Valve Endoprosthesis Study (NCT04943172)
The Hancock Jaffe Surgical Antireflux Venous Valve Endoprosthesis (SAVVE) Study
🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol Sponsor: Hancock Jaffe Laboratiores, Inc
🩺 Plain-English Summary (8th-Grade Level)
A prospective, non blinded, single arm, multicenter study designed to assess the safety and effectiveness of the bioprosthetic, VenoValve, which is surgically implanted into the deep venous system for treatment of patients with deep venous valvular insufficiency ( C4b-C6 patients).
Who can join: Review the eligibility criteria below.
Location: University of Alabama at Birmingham — Birmingham, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (29 Sites)
Showing the first 25 of 29 sites.
- University of Alabama at Birmingham — Birmingham, Alabama
- Pima Heart and Vascular — Tucson, Arizona
- Cedars-Sinai Medical Center — Beverly Hills, California
- Yale school of Medicine — New Haven, Connecticut
- Coastal Vascular — Fort Walton Beach, Florida
- Miami Vascular Specialists — Miami, Florida
- University of Chicago — Chicago, Illinois
- Indiana University — Indianapolis, Indiana
- University of Louisville — Louisville, Kentucky
- Massachusetts General Hospital — Boston, Massachusetts
- Henry Ford Health System — Detroit, Michigan
- Saint Louis University — St Louis, Missouri
- Englewood Health — Englewood, New Jersey
- Albany Medical Center — Albany, New York
- Kaleidahealth — Buffalo, New York
- NYU Langone — New York, New York
- Mount Sinai Hospital — New York, New York
- Stony Brook Medicine — New York, New York
- St. Peter's Vascular Associates — Troy, New York
- University of North Carolina — Chapel Hill, North Carolina
- TriHealth — Cincinnati, Ohio
- University Hospitals Cleveland Medical Center — Cleveland, Ohio
- Jobst Vascular Institute / Promedica Toledo Hospital — Toledo, Ohio
- UPMC — Pittsburgh, Pennsylvania
- Lankenau Medical Center — Wynnewood, Pennsylvania
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Deep Venous Insufficiency (Diagnosis) clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.