The Safety, Tolerability, and Effectiveness of Quetiapine in Postpartum Depression (NCT04950868)
A Pilot Study on the Safety, Tolerability, and Effectiveness of Quetiapine in Postpartum Depression
π©Ί Plain-English Summary (8th-Grade Level)
Postpartum depression is a serious disorder that affects approximately 14% of women who have recently given birth. Postpartum depression is either an episode of major depressive disorder (only low periods) or bipolar disorder (periods of lows and highs). Untreated postpartum depression can negatively affect the mother, the infant and the family. Antidepressants are the most used treatmentsΝΎ however, for many women these drugs are not useful, resulting in a pressing need for effective treatments for postpartum depression. Lack of sleep is common after delivery and can trigger depression in some women. Quetiapine, a drug used for bipolar disorder, major depressive disorder and occasionally sleeplessness has not been well studied in postpartum depression. This study aims to find out how mothers tolerate the drug and whether it is effective for postpartum depression. Results of this study may help investigators carry out a larger study comparing quetiapine and placebo (a sugar pill) in postpartum depression.
Who can join: Review the eligibility criteria below.
Location: Parkwood Institute β London, Ontario
Age range: 18 Years to 45 Years
π§ͺ Interventions in This Study
π "Do I Qualify?" β 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria β
π All Participating Trial Locations (1 Sites)
- Parkwood Institute β London, Ontario
π° Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Postpartum Depression
- Preventing Postpartum Depression in Immigrant Latinas β Baltimore, Maryland
- Public Health Nurse-Peer Co-Led Group Cognitive Behavioral Therapy for Postpartum Depression β Hamilton, Ontario
- The Maternal Well-Being Study β Amarillo, Texas
- CBT for Postpartum Depression and Infant Emotion Regulation β Hamilton, Ontario
- Whole-Body Hyperthermia for Mood and Anxiety Disorders β New York, New York
Explore by condition: All Postpartum Depression clinical trials
π‘ How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.