🏛️ Verified NIH Record • Updated 2025-01-17
Osteosarcoma Maintenance Therapy With OST31-164 (NCT04974008)
An Open-Label Phase 2 Study of Maintenance Therapy With OST31-164 After Resection of Recurrent Osteosarcoma
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Emerald Clinical Inc.
🩺 Plain-English Summary (8th-Grade Level)
Up to 45 Patients aged 12 to 39 with osteosarcoma (bone cancer) that had recurred in the lungs and has recently been surgically removed will be enrolled. Patients will receive OST31-164 infusions every 3 weeks over 48 weeks and be followed after that for 3 years.
Who can join: Review the eligibility criteria below.
Location: Kaiser Permanente Downey Medical Center — Los Angeles, California
Age range: 12 Years to 39 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (21 Sites)
- Kaiser Permanente Downey Medical Center — Los Angeles, California
- Children's Hospital of Orange County — Orange, California
- Rady Children's Hospital — San Diego, California
- Children's Hospital of Colorado — Aurora, Colorado
- Connecticut Children's — Hartford, Connecticut
- Nemours/ Alfred I duPont Hospital for Children — Wilmington, Delaware
- Johns Hopkins All Children's Hospital — St. Petersburg, Florida
- Children's Healthcare of Atlanta — Atlanta, Georgia
- Ann & Robert H. Lurie Children's Hospital of Chicago — Chicago, Illinois
- Johns Hopkins Medical Center — Baltimore, Maryland
- Dana-Farber Cancer Institute — Boston, Massachusetts
- University of Minnesota/Masonic Cancer Center — Minneapolis, Minnesota
- Hackensack University Medical Center — Hackensack, New Jersey
- Montefiore Medical Center — The Bronx, New York
- Nationwide Children's Hospital — Columbus, Ohio
- Oregon Health & Science University — Portland, Oregon
- Children's Hospital of Philadelphia — Philadelphia, Pennsylvania
- UPMC Children's Hospital of Pittsburgh — Pittsburgh, Pennsylvania
- St. Jude Children's Research Hospital — Memphis, Tennessee
- UT Southwestern Medical Center — Dallas, Texas
- Seattle Children's Hospital — Seattle, Washington
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.