GWICTIC: NAC Mechanistic Study in Gulf War Veterans (NCT04987775)
Mechanisms of Oxidative Stress During N-Acetyl Cysteine (NAC) Supplementation in Veterans With Gulf War Illness (GWI)
🩺 Plain-English Summary (8th-Grade Level)
This mechanistic study will test if NAC affects chronic oxidative stress and depletion of antioxidants in GWI participants. Blood specimen collection and neuroimaging will be used to determine whether NAC affects serum glutathione (GSH) concentration and oxidative stress in the CNS when compared to placebo.
Who can join: Review the eligibility criteria below.
Location: VA Palo Alto Health Care System War Related Illness and Injury Study Center — Palo Alto, California
Age range: 47 Years to 70 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (7 Sites)
- VA Palo Alto Health Care System War Related Illness and Injury Study Center — Palo Alto, California
- Nova Southeastern University — Fort Lauderdale, Florida
- Boston University Medical School — Boston, Massachusetts
- VA New Jersey Health Care System War Related Illness and Injury Study Center — East Orange, New Jersey
- Weill Cornell Medical College — New York, New York
- RTI International — Durham, North Carolina
- Michael E. DeBakey VA Medical Center — Houston, Texas
📞 Contact the Study Coordinator
Phone: (954) 262-2855
Email: nklimas@nova.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Gulf War Syndrome
- Pycnogenol (French Maritime Pine Bark) for the Treatment of Gulf War Illness — Birmingham, Alabama
- Growth Hormone Replacement in Veterans With GWI and AGHD (GWIT) — Houston, Texas
- Coenzyme Q10 for Gulf War Illness: A Replication Study — La Jolla, California
- Validating Gulf War Illness Blood Biomarkers — Palo Alto, California
- Cranial Electrotherapy Stimulation and Brain Imaging for Gulf War Syndrome — Atlanta, Georgia
Explore by condition: All Gulf War Syndrome clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.