Surgical Treatments for Postamputation Pain (NCT05009394)
🩺 Plain-English Summary (8th-Grade Level)
This is a double-blind randomised controlled trial (RCT) which compares the effectiveness of three surgical techniques for alleviating residual limb pain (RLP), neuroma pain and phantom limb pain (PLP). The three surgical treatments are Targeted Muscles Reinnervation (TMR), Regenerative Peripheral Nerve Interface (RPNI), and an active control (neuroma excision and muscle burying). Patients will be follow-up for 4 years.
Who can join: Review the eligibility criteria below.
Location: Northwestern Memorial Hospital — Chicago, Illinois
Age range: 18 Years
🧪 Interventions in This Study
- Targeted Muscle Reinnervation (TMR) (PROCEDURE)
- Regenerative Peripheral Nerve Interface (RPNI) (PROCEDURE)
- Standard neuroma treatment, neuroma excision, and muscle burying (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (9 Sites)
- Northwestern Memorial Hospital — Chicago, Illinois
- Massachusetts General Hospital — Boston, Massachusetts
- University of Michigan Health System — Ann Arbor, Michigan
- Dandenong Hospital, Monash Health — Melbourne,
- University of Alberta Hospital — Edmonton, Alberta
- Worker Hospital — Santiago,
- Rizzoli Orthopedic Institute — Bologna, Emilia-Romagna
- Sahlgrenska University Hospital — Mölndal, Västra Götaland County
- NHS Lothian, NHS Clyde & Greater Glasgow, and NHS Grampian — Edinburgh,
📞 Contact the Study Coordinator
Phone: +46708461065
Email: maxortizc@outlook.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Residual Limb Pain clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.