๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-08-14

A Comparison of TULSA Procedure vs. Radical Prostatectomy in Participants With Localized Prostate Cancer (NCT05027477)

Customized Ablation of the Prostate With the TULSA Procedure Against Radical Prostatectomy Treatment: a Randomized Controlled Trial for Localized Prostate Cancer (CAPTAIN)

๐Ÿ”ต Active, Not Recruiting Observational / Diagnostic โš™๏ธ Medical Device Protocol Sponsor: Profound Medical Inc.

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

Men with localized, intermediate risk prostate cancer will be randomized to undergo either radical prostatectomy or the TULSA procedure, with a follow-up of 10 years in this multi-centered randomized control trial. This study will determine whether the TULSA procedure is as effective and more safe compared to radical prostatectomy.

Who can join: Review the eligibility criteria below.

Location: Arizona State Urological Institute โ€” Chandler, Arizona

Age range: 40 Years to 80 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (22 Sites)

  • Arizona State Urological Institute โ€” Chandler, Arizona
  • East Valley Urological Center โ€” Mesa, Arizona
  • Investigate MD โ€” Scottsdale, Arizona
  • Atlantic Urology Medical Group โ€” Long Beach, California
  • Urology Group of Southern California โ€” Los Angeles, California
  • University of California, Los Angeles โ€” Los Angeles, California
  • Comprehensive Urology Medical Group โ€” Los Angeles, California
  • Alarcon Urology Center โ€” Montebello, California
  • Pasadena Urological Medical Group โ€” Pasadena, California
  • Stanford Cancer Center โ€” Stanford, California
  • Yale Cancer Center โ€” New Haven, Connecticut
  • Mayo Clinic Jacksonville โ€” Jacksonville, Florida
  • Sarasota Memorial Health Care System โ€” Sarasota, Florida
  • Indiana University โ€” Indianapolis, Indiana
  • Johns Hopkins School of Medicine โ€” Baltimore, Maryland
  • Mayo Clinic โ€” Rochester, Minnesota
  • Cleveland Clinic โ€” Cleveland, Ohio
  • The University of Texas Southwestern Medical Center โ€” Dallas, Texas
  • The Urology Place โ€” San Antonio, Texas
  • Lawson Health Research Institute, London Health Sciences Centre โ€” London, Ontario
  • Sunnybrook Research Institute โ€” Toronto, Ontario
  • Turku University Hospital/TYKS โ€” Turku, Southwest Finland

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Prostate Cancer clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—