Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases (NCT05034497)
A Multicenter Phase 1 Clinical Study to Determine the Maximum Tolerated Dose/Maximum Feasible Dose, Safety,& Efficacy of Single Dose Rhenium-186 NanoLiposome (186RNL) Administered Via Intraventricular Catheter for Leptomeningeal Metastases
🩺 Plain-English Summary (8th-Grade Level)
This is an open-label Phase I clinical study that will administer a single dose of 186RNL via intraventricular catheter for treatment of Leptomeningeal Metastases (LM).
Who can join: Review the eligibility criteria below.
Location: Northwestern Memorial Hospital Olson Pavilion — Chicago, Illinois
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (6 Sites)
- Northwestern Memorial Hospital Olson Pavilion — Chicago, Illinois
- Northshore University Hospital — Manhasset, New York
- Lenox Hill Hospital — New York, New York
- Ohio State University Hospital — Columbus, Ohio
- Universiy of Texas Southwestern Medical Center — Dallas, Texas
- UT Health Science Center San Antonio / Mays Cancer Center — San Antonio, Texas
📞 Contact the Study Coordinator
Phone: (855) 692-6482
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Leptomeningeal Metastasis
- Study of Craniospinal Irradiation With Linac Based Volumetric Modulated Arc Therapy (VMAT) for Patients With Leptomeningeal Metastasis — New York, New York
- BRain-AVOidant Proton Craniospinal Irradiation for Leptomeningeal Metastases From Solid Tumor Malignancies — Miami, Florida
- Wearable-Triggered Digital Safety Net for Real-Time Monitoring & Intervention in Leptomeningeal Metastasis — Cleveland, Ohio
- Standardized Clinical Assessment of Patients With Leptomeningeal Metastasis — Houston, Texas
- Multiple Dose Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases — San Antonio, Texas
Explore by condition: All Leptomeningeal Metastasis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.