Changing the Natural History of Type 2 Diabetes ("CHANGE" Study) (NCT05040087)
๐ฉบ Plain-English Summary (8th-Grade Level)
Diabetes is a disorder of high blood glucose, that tends to get worse; over time, patients need more and more drugs. This pattern is caused by overwork of the body's insulin-producing ฮฒ-cells, because patients' glucose levels are typically above normal; if the investigators kept glucose levels normal - reducing ฮฒ-cell work - the investigators might be able to keep the disease from getting worse. This trial is aimed to show that adjusting the drugs to keep glucose levels normal, can help to preserve ฮฒ-cell function compared to usual diabetes care, possibly reduce the tendency to develop the eye and kidney complications of diabetes, and might also be more cost-effective than usual care.
Who can join: Review the eligibility criteria below.
Location: Atlanta VA Medical Center โ Decatur, Georgia
Age range: 40 Years to 75 Years
๐งช Interventions in This Study
- Intensification of diabetes medication based largely on HbA1c levels (OTHER)
- Intensification of diabetes medication based on glucose levels (OTHER)
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (1 Sites)
- Atlanta VA Medical Center โ Decatur, Georgia
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Type 2 Diabetes
- Continuous Glucose Monitoring System Feasibility in Youth With T2D โ San Francisco, California
- Diabetes Nutrition Education and Healthy Food Resource for AIANs With T2D โ Oklahoma City, Oklahoma
- Personalized Nutrition Therapy Using Continuous Glucose Monitoring to Improve Outcomes in Type 2 Diabetes Mellitus โ Minneapolis, Minnesota
- Diabetes Medical Nutrition Therapy in Southeastern African American Women โ Nashville, Tennessee
- E3 Diabetes - Closing the Gap in Diabetes Control โ Chicago, Illinois
- Recreational Basketball to Increase Participation in Diabetes Prevention โ Atlanta, Georgia
Explore by condition: All Type 2 Diabetes clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.