A Study of Acalabrutinib Plus Venetoclax Versus Venetoclax Plus Obinutuzumab in Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (NCT05057494)

🧪 Interventions in This Study

• Acalabrutinib (DRUG)
• Venetoclax (DRUG)
• Obinutuzumab (DRUG)

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (37 Sites)

Showing the first 25 of 37 sites.

• Research Site — Tucson, Arizona
• Research Site — La Jolla, California
• Research Site — Longmont, Colorado
• Research Site — Jacksonville, Florida
• Research Site — Boston, Massachusetts
• Research Site — Rochester, Minnesota
• Research Site — St Louis, Missouri
• Research Site — Buffalo, New York
• Research Site — New Hyde Park, New York
• Research Site — New York, New York
• Research Site — Rochester, New York
• Research Site — Charlotte, North Carolina
• Research Site — Cleveland, Ohio
• Research Site — Eugene, Oregon
• Research Site — Nashville, Tennessee
• Research Site — Salt Lake City, Utah
• Research Site — Charlottesville, Virginia
• Research Site — Seattle, Washington
• Research Site — Seattle, Washington
• Research Site — Clayton,
• Research Site — Nedlands,
• Research Site — Waratah,
• Research Site — Hradec Králové,
• Research Site — Ostrava - Poruba,
• Research Site — Pilsen,

💰 Cost, Insurance & Patient Rights

• 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
• Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
• Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

• A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia — Rochester, Minnesota

Explore by condition: All Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma clinical trials

💡 How to Participate

1. Check the checklist above to see if you may qualify.
2. Review the official NIH record below to find the coordinating site.
3. Ask about the visit schedule, what is covered at no cost, and any travel support.
4. Confirm with your own doctor before making a decision.