🏛️ Verified NIH Record • Updated 2026-08-25
TheraSphere With Durvalumab and Tremelimumab for HCC (NCT05063565)
An Open-Label, Prospective, Multi-Center Clinical Trial to Evaluate the Efficacy and Safety of TheraSphere™ Followed by Durvalumab (Imfinzi®) With Tremelimumab (Imjudo®) for Hepatocellular Carcinoma (HCC)
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Boston Scientific Corporation
🩺 Plain-English Summary (8th-Grade Level)
The objective of the ROWAN clinical study is to assess the efficacy of local tumor control in HCC patients who receive TheraSphere followed by durvalumab and tremelimumab.
Who can join: Review the eligibility criteria below.
Location: University of California San Diego — San Diego, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (35 Sites)
Showing the first 25 of 35 sites.
- University of California San Diego — San Diego, California
- University of California San Francisco — San Francisco, California
- Georgetown University — Washington D.C., District of Columbia
- MedStar Washington Hospital Center — Washington D.C., District of Columbia
- Mayo Clinic — Jacksonville, Florida
- Rush University Medical Center — Chicago, Illinois
- University of Chicago Hospital — Chicago, Illinois
- Ochsner Clinic Foundation — New Orleans, Louisiana
- University of Minnesota — Minneapolis, Minnesota
- Washington University (Barnes-Jewish Hospital) — St Louis, Missouri
- Columbia University Irving Medical Center — New York, New York
- Intermountain Health — Salt Lake City, Utah
- CHU Nantes — Rennes, Cedex
- Hôpital Beaujon — Clichy, Hauts De Seine
- CHU Grenoble — Grenoble, Isere
- CHU de Bordeaux - Hôpital Haut-Lévêque — Clermont-Ferrand,
- Chu Henri Mondor — Créteil,
- Chru De Lille — Lille,
- CHU Montpellier — Montpellier,
- CHU Angers - Hôpital Hôtel Dieu — Nantes,
- CRLCC Eugene Marquis — Rennes,
- Hopital Paul Brousse — Villejuif,
- National Cancer Institute of Milan, Italy — Milan,
- IRCCS - Regina Elena Cancer Institute — Roma,
- Azienda Sanitaria Universitaria Integrata Friuli Centrale (ASU FC) — Udine,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- Feasibility and Efficacy of Perioperative Nivolumab With or Without Relatlimab for Patients With Potentially Resectable Hepatocellular Carcinoma (HCC) — Baltimore, Maryland
- Blood Salvage in Orthotopic Liver Transplantation With HCC — Toronto, Ontario
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Explore by condition: All Hepatocellular Carcinoma clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.