Screening Algorithms for Cervical and Anal High-Grade Squamous Intraepithelial Lesions in People With HIV in Mexico and Puerto Rico (NCT05074264)
Optimization of Screening Algorithms for Cervical and Anal High-Grade Squamous Intraepithelial Lesions in People Living With HIV in Mexico and Puerto Rico
🩺 Plain-English Summary (8th-Grade Level)
This clinical trial aims to find what different tests work best to find high-grade squamous intraepithelial lesions (HSIL) in the cervix or anus in patients living with human immunodeficiency virus (HIV). Patients with HIV are at high risk of becoming infected with human papillomavirus (HPV) in the cervix or anus where it can turn into cancer over several years. HPV causes changes to the cervix and anus, known as HSIL. This means that there is an area of abnormal tissue on the top layers of the cervix or anus. It is considered cervical or anal cancer if the abnormality spreads down into the layers of tissue below the top. If found early, many cases of HSIL can be treated before turning into cancer. Screening for cervical or anal cancer detection or HSIL associated with HPV may result in earlier treatment, if necessary, for patients living with HIV.
Who can join: Review the eligibility criteria below.
Location: Condesa Specialized Clinic — Mexico City, Mexico City
Age range: 21 Years
🧪 Interventions in This Study
- Biopsy (PROCEDURE)
- Biospecimen Collection - Anal (PROCEDURE)
- Biospecimen Collection - Cervical (PROCEDURE)
- Colposcopy (PROCEDURE)
- High Resolution Anoscopy (PROCEDURE)
- Imaging Technique (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (4 Sites)
- Condesa Specialized Clinic — Mexico City, Mexico City
- Condesa Iztapalapa Specialized Clinic — Mexico City, Mexico City
- Instituto Nacional de Cancerologia (INCan) — Mexico City, Mexico City
- University of Puerto Rico Comprehensive Cancer Center — San Juan, PR
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in AIDS-Related Anal Carcinoma
- Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer — San Francisco, California
Explore by condition: All AIDS-Related Anal Carcinoma clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.