A Study of Teclistamab in Combination With Daratumumab Subcutaneously (SC) (Tec-Dara) Versus Daratumumab SC, Pomalidomide, and Dexamethasone (DPd) or Daratumumab SC, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (NCT05083169)
A Phase 3 Randomized Study Comparing Teclistamab in Combination With Daratumumab SC (Tec-Dara) Versus Daratumumab SC, Pomalidomide, and Dexamethasone (DPd) or Daratumumab SC, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma
๐ฉบ Plain-English Summary (8th-Grade Level)
The purpose of this study is to compare the efficacy of teclistamab daratumumab (Tec-Dara) with daratumumab subcutaneously (SC) in combination with pomalidomide and dexamethasone (DPd) or daratumumab SC in combination with bortezomib and dexamethasone (DVd).
Who can join: Review the eligibility criteria below.
Location: University of Alabama Birmingham โ Birmingham, Alabama
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (176 Sites)
Showing the first 25 of 176 sites.
- University of Alabama Birmingham โ Birmingham, Alabama
- City of Hope โ Duarte, California
- Stanford University Medical Center โ Stanford, California
- Yale University โ New Haven, Connecticut
- Emory University Winship Cancer Institute โ Atlanta, Georgia
- Tufts Medical Center โ Boston, Massachusetts
- Henry Ford Hospital โ Detroit, Michigan
- Henry Ford Health System โ Southfield, Michigan
- Cleveland Clinic โ Cleveland, Ohio
- West Penn Hospital โ Pittsburgh, Pennsylvania
- University of Pittsburgh Medical Center โ Pittsburgh, Pennsylvania
- Medical University of South Carolina โ Charleston, South Carolina
- Baptist Cancer Center โ Memphis, Tennessee
- Vanderbilt Ingram Cancer Center โ Nashville, Tennessee
- University of Texas Southwestern Medical Center โ Dallas, Texas
- Huntsman Cancer Institute โ Salt Lake City, Utah
- Fred Hutchinson Cancer Center โ Seattle, Washington
- University of Wisconsin Carbone Cancer Center โ Madison, Wisconsin
- Hospital Italiano de Buenos Aires โ Buenos Aires,
- Hospital Aleman โ CABA,
- Hospital Privado Centro Medico de Cordoba โ Cรณrdoba,
- ZAS Cadix โ Antwerp,
- AZ St.-Jan Brugge-Oostende AV โ Bruges,
- UZ Gent โ Ghent,
- Hopital de Jolimont โ Haine Saint Paul La Louviere,
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Multiple Myeloma
- Ixazomib + Pomalidomide + Dexamethasone In MM โ Boston, Massachusetts
- A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma โ Birmingham, Alabama
- Multiple Myeloma Outcomes Based on Maintenance Therapy Post Autologous Stem Cell Transplant โ Tampa, Florida
- MagnetisMM-3: Study Of Elranatamab (PF-06863135) Monotherapy in Participants With Multiple Myeloma Who Are Refractory to at Least One PI, One IMiD and One Anti-CD38 mAb โ Beverly Hills, California
- A Study of CLN-619 (Anti-MICA/MICB Antibody) in Patients With Relapsed and Refractory Multiple Myeloma โ Phoenix, Arizona
- A Study of Carfilzomib, Lenalidomide, Vorinostat, and Dexamethasone in Relapsed and/or Refractory Multiple Myeloma โ Hackensack, New Jersey
Explore by condition: All Multiple Myeloma clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.