ROSE-Longitudinal Assessment With Neuroimaging (NCT05089331)
Recovery and Outcomes From Stroke-Longitudinal Assessment With Neuroimaging
๐ฉบ Plain-English Summary (8th-Grade Level)
The investigators will perform follow-up on 250 of 500 cases recruited into the ROSE study of cases with deep and lobar intracerebral hemorrhage to perform advanced neuroimaging at 12-24 months post stroke, and evaluations of motor and cognitive function at baseline, 6 months after baseline, and 12 months after baseline to determine predictors of recovery, progressive cognitive or functional impairment. The investigators propose to leverage the recruitment, DNA, RNA-seq and baseline advanced neuroimaging cohort of ROSE to obtain long-term neuroimaging and identical assessments longitudinally to address critical questions regarding the progressive decline of patients 12 to 24 months post intracerebral hemorrhage (ICH) with long term cognitive follow-up to 36 months on average. This proposal would represent the largest, and longest advanced neuroimaging and RNA-sequencing evaluation after ICH to date.
Who can join: Review the eligibility criteria below.
Location: University of Illinois Chicago โ Chicago, Illinois
Age range: 18 Years
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (7 Sites)
- University of Illinois Chicago โ Chicago, Illinois
- Baptist Health Louisville โ Louisville, Kentucky
- University of Maryland โ Baltimore, Maryland
- Columbia University โ New York, New York
- Duke University โ Durham, North Carolina
- University of Cincinnati โ Cincinnati, Ohio
- Houston Methodist โ Houston, Texas
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Intracerebral Hemorrhage
- Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial โ Birmingham, Alabama
- Regulating Blood Pressure During Recovery From Intracerebral Hemorrhage and Ischemic Stroke โ New Haven, Connecticut
- Biomarker and Edema Attenuation in IntraCerebral Hemorrhage (BEACH) โ Birmingham, Alabama
- Synergistic Minimally Invasive Surgery and Deferoxamine in ICH โ Chicago, Illinois
- Auricular VNS Following Intracerebral Hemorrhage โ St Louis, Missouri
Explore by condition: All Intracerebral Hemorrhage clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.