🏛️ Verified NIH Record • Updated 2024-05-31
Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1) (NCT05103358)
A Phase 2 Multi-center Open-label Basket Trial of Nab-sirolimus for Adult and Adolescent Patients With Malignant Solid Tumors Harboring Pathogenic Inactivating Alterations in TSC1 or TSC2 Genes.
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Aadi Bioscience, Inc.
🩺 Plain-English Summary (8th-Grade Level)
A Phase 2 multi-center open-label basket trial of nab-sirolimus for adult and adolescent patients with malignant solid tumors harboring pathogenic inactivating alterations in TSC1 or TSC2 genes
Who can join: Review the eligibility criteria below.
Location: Alabama Oncology — Birmingham, Alabama
Age range: 12 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (166 Sites)
Showing the first 25 of 166 sites.
- Alabama Oncology — Birmingham, Alabama
- Southern Cancer Center — Mobile, Alabama
- Arizona Oncology Associates — Goodyear, Arizona
- Honor Health — Phoenix, Arizona
- Arizona Oncology Associates — Prescott Valley, Arizona
- Yuma Regional Medical Center — Yuma, Arizona
- PCR Oncology — Arroyo Grande, California
- Nextgen Oncology — Beverly Hills, California
- City of Hope — Duarte, California
- Providence Medical Foundation (Fullerton) — Fullerton, California
- MemorialCare — Long Beach, California
- USC Norris Comprehensive Cancer Center — Los Angeles, California
- UCLA - Jonsson Comprehensive Cancer Center — Los Angeles, California
- Providence Medical Foundation (Napa) — Napa, California
- Hoag Memorial Hospital Presbyterian — Newport Beach, California
- Sharp HealthCare — San Diego, California
- UCSF Helen Diller Family Comprehensive Cancer Center — San Francisco, California
- Ridley-Tree Cancer Center — Santa Barbara, California
- Sarcoma Oncology Research Center — Santa Monica, California
- Providence Medical Foundation — Santa Rosa, California
- Stanford Cancer Center — Stanford, California
- The Oncology Institute of Hope & Innovation — Whittier, California
- Rocky Mountain Cancer Centers — Aurora, Colorado
- Rocky Mountain Cancer Centers — Boulder, Colorado
- Rocky Mountain Cancer Centers — Colorado Springs, Colorado
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.