๐๏ธ Verified NIH Record โข Updated 2026-03-06
An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms (NCT05123365)
๐ข Recruiting Phase1 / Phase2 ๐ Investigational Drug / Biologic Sponsor: University of California, Irvine
๐ฉบ Plain-English Summary (8th-Grade Level)
This is a phase I/II study evaluating the optimal dose of N-acetylcysteine (N-AC) in patients with myeloproliferative neoplasms (MPN).
Who can join: Review the eligibility criteria below.
Location: University of California, Irvine โ Irvine, California
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (2 Sites)
- University of California, Irvine โ Irvine, California
- Chao Family Comprehensive Cancer Center, University of California, Irvine โ Orange, California
๐ Contact the Study Coordinator
Phone: (714) 456-8000
Email: agf@hs.uci.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Myeloproliferative Neoplasm
- A Study Evaluating Safety and Tolerability, and Pharmacokinetics of Navitoclax Monotherapy and in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasm โ Duarte, California
- Phase I Trial of Pacritinib in Combination With Venetoclax and Azacitidine for the Treatment of Accelerated and Blast Phase Myeloproliferative Neoplasms โ Buffalo, New York
- Evaluation of the Pathobiology of CALR-mutated MPN Cells โ Charlotte, North Carolina
- Study of Venetoclax and Azacitidine in Advanced BCR-ABL Negative Myeloproliferative Neoplasms โ Toronto, Ontario
Explore by condition: All Myeloproliferative Neoplasm clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.