๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-11

A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies (NCT05123482)

A Phase I/IIa Multi-center, Open-label Master Protocol Dose Escalation and Expansion Study of AZD8205 as Monotherapy and in Combination With Anticancer Agents in Participants With Advanced Solid Tumors (BLUESTAR)

๐ŸŸข Recruiting Phase1 / Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: AstraZeneca

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This research study is studying a new compound, AZD8205, as a possible treatment for advanced or metastatic solid tumours alone or in combination with anti-cancer agents

Who can join: Review the eligibility criteria below.

Location: Research Site โ€” Duarte, California

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (67 Sites)

Showing the first 25 of 67 sites.

  • Research Site โ€” Duarte, California
  • Research Site โ€” Irvine, California
  • Research Site โ€” Santa Monica, California
  • Research Site โ€” Santa Rosa, California
  • Research Site โ€” Shreveport, Louisiana
  • Research Site โ€” Baltimore, Maryland
  • Research Site โ€” Boston, Massachusetts
  • Research Site โ€” St Louis, Missouri
  • Research Site โ€” Albuquerque, New Mexico
  • Research Site โ€” Commack, New York
  • Research Site โ€” New York, New York
  • Research Site โ€” Charlotte, North Carolina
  • Research Site โ€” Pittsburgh, Pennsylvania
  • Research Site โ€” Houston, Texas
  • Research Site โ€” Clayton,
  • Research Site โ€” Melbourne,
  • Research Site โ€” Nedlands,
  • Research Site โ€” Anderlecht,
  • Research Site โ€” Leuven,
  • Research Site โ€” Calgary, Alberta
  • Research Site โ€” Vancouver, British Columbia
  • Research Site โ€” Ottawa, Ontario
  • Research Site โ€” Toronto, Ontario
  • Research Site โ€” Montreal, Quebec
  • Research Site โ€” Beijing,

๐Ÿ“ž Contact the Study Coordinator

Phone: (877) 240-9479

Email: information.center@astrazeneca.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

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๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—