🏛️ Verified NIH Record • Updated 2026-07-01
The Zonisamide and Reinforcement for Reducing Alcohol Use (ZARRA) Study (NCT05134857)
Zonisamide for the Treatment of Alcohol Use Disorder in the Addiction Neuroclinical Assessment Framework
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Washington State University
🩺 Plain-English Summary (8th-Grade Level)
A phase II randomized, double-blind, placebo-controlled clinical trial (RCT) to evaluate the ability of zonisamide (ZON) to decrease alcohol use among treatment-seeking adults with an alcohol use disorder (AUD).
Who can join: Review the eligibility criteria below.
Location: Washington State University — Spokane, Washington
Age range: 18 Years to 65 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Washington State University — Spokane, Washington
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Alcohol Use Disorder (AUD)
- PsiloStudy: Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD) — Seattle, Washington
- Ibudilast for Treating Alcohol Use Disorder — Philadelphia, Pennsylvania
- Semaglutide Dose Effects on Metabolic and Stress Hormone, Craving and Alcohol Use Outcomes — New Haven, Connecticut
- Social Identity Mapping for Adolescent Recovery — Boston, Massachusetts
- Cannabidiol as an Adjunct Treatment for Alcohol Withdrawal and Craving — Baltimore, Maryland
Explore by condition: All Alcohol Use Disorder (AUD) clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.