🏛️ Verified NIH Record • Updated 2026-02-09
Risk of Metabolic Adaptation After Weight Loss (NCT05139420)
Biomarkers of Increased Risk of Developing Metabolic Adaptation to Weight Loss
🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol Sponsor: Medical College of Wisconsin
🩺 Plain-English Summary (8th-Grade Level)
This study aims at identifying the neurohormonal biomarkers that characterize individuals at risk of greater metabolic adaptation to weight loss, a disproportionate decline in resting metabolic rate during and after weight loss.
Who can join: Review the eligibility criteria below.
Location: Medical College of Wisconsin — Milwaukee, Wisconsin
Age range: 18 Years to 50 Years
🧪 Interventions in This Study
- lifestyle intervention with meal replacement program (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Medical College of Wisconsin — Milwaukee, Wisconsin
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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Explore by condition: All Weight Loss clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.