๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-04-27

Alpelisib And Sacituzumab Govitecan For Treatment Of Breast Cancer (NCT05143229)

Phase I Trial Of Alpelisib Plus Sacituzumab Govitecan In Patients With Metastatic Or Locally Recurrent HER2-Negative Breast Cancer

๐Ÿ”ต Active, Not Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: University of Kansas Medical Center

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This study evaluates the safety and efficacy of sacituzumab govitecan plus alpelisib for treatment of metastatic or locally recurrent HER2-negative breast cancer.

Who can join: Review the eligibility criteria below.

Location: The University of Kansas Clinical Research Center โ€” Fairway, Kansas

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (7 Sites)

  • The University of Kansas Clinical Research Center โ€” Fairway, Kansas
  • The University of Kansas Cancer Center - Overland Park โ€” Overland Park, Kansas
  • The University of Kansas Cancer Center - Indian Creek โ€” Overland Park, Kansas
  • The University of Kansas Cancer Center โ€” Westwood, Kansas
  • The University of Kansas Cancer Center - North Kansas City Hospital โ€” Kansas City, Missouri
  • The University of Kansas Cancer Center - North โ€” Kansas City, Missouri
  • The University of Kansas Cancer Center - Lee's Summit โ€” Lee's Summit, Missouri

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Breast Cancer clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—