A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189, in 10- to 30-Year-Old Healthy Adolescents and Adults (NCT05164094)
A Phase 1/2, Randomized, Observer-Blind, Placebo-Controlled, Dose-Ranging Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189, in 10- to 30-Year-Old Healthy Adolescents and Adults
🩺 Plain-English Summary (8th-Grade Level)
The main objective of Part A of this trial is to evaluate the safety and reactogenicity of mRNA-1189 in 18- to 30-year-old healthy adults, the main objective of Part B is to evaluate the safety and reactogenicity of mRNA-1189 in 12- to \<18-year-old healthy EBV-seronegative adolescents, and the main objective of Part C is to evaluate the safety and reactogenicity of mRNA-1189 in 10- to 21-year-old healthy adolescents and adults.
Who can join: Review the eligibility criteria below.
Location: Medical Affiliated Research Institute — Huntsville, Alabama
Age range: 10 Years to 30 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (65 Sites)
Showing the first 25 of 65 sites.
- Medical Affiliated Research Institute — Huntsville, Alabama
- Smart Cures Clinical Research — Anaheim, California
- Benchmark Research - Colton - HyperCore - PPDS — Colton, California
- Fomat Medical Research — Oxnard, California
- Center For Clinical Trials LLC -Paramount — Paramount, California
- Artemis Institute For Clinical Research LLC - Riverside - Headlands - PPDS — Riverside, California
- Peninsula Research Associates - Headlands Research - PPDS — Rolling Hills, California
- Velocity Clinical Research - Banning - PPDS — San Bernardino, California
- Acclaim Clinical Research — San Diego, California
- California Research Foundation - 4180 Ruffin Rd — San Diego, California
- Orange County Research Center — Tustin, California
- CenExel iResearch, LLC — Hollywood, Florida
- Jacksonville Center For Clinical Research - ERN - PPDS — Jacksonville, Florida
- iResearch Savannah - CenExel - PPDS — Savannah, Georgia
- Velocity Clinical Research - Savannah — Savannah, Georgia
- Clinical Research Atlanta - Headlands - PPDS — Stockbridge, Georgia
- Velocity Clinical Research — Meridian, Idaho
- Olivo Medical and Wellness Center — Chicago, Illinois
- DM Clinical Research — River Forest, Illinois
- Velocity Clinical Research — Valparaiso, Indiana
- Velocity Clinical Research - Sioux City — Sioux City, Iowa
- Alliance for Multispecialty Research, LLC - El Dorado - PPDS — El Dorado, Kansas
- Johnson County Clin-Trials — Lenexa, Kansas
- Alliance for Multispecialty Research LLC, East Wichita — Wichita, Kansas
- Michael W Simon MD, PSC — Lexington, Kentucky
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Epstein-Barr Virus Infection
Explore by condition: All Epstein-Barr Virus Infection clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.