A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma (NCT05169515)
A Phase Ib, Open-Label, Multicenter Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Patients With B-Cell Non-Hodgkin Lymphoma
๐ฉบ Plain-English Summary (8th-Grade Level)
This study will evaluate the safety, efficacy, and pharmacokinetics of mosunetuzumab or glofitamab in combination with CELMoDs (CC-220 and/or CC-99282) in participants with B-cell NHL.
Who can join: Review the eligibility criteria below.
Location: UCSF/Hematology, Blood & Marrow Transplant, And Cellular Therapy (HBC) Program โ San Francisco, California
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (25 Sites)
- UCSF/Hematology, Blood & Marrow Transplant, And Cellular Therapy (HBC) Program โ San Francisco, California
- University of Colorado โ Aurora, Colorado
- Moffitt Cancer Center โ Tampa, Florida
- The University of Chicago โ Chicago, Illinois
- Levine Cancer Institute โ Charlotte, North Carolina
- UT MD Anderson Cancer Center โ Houston, Texas
- Soroka โ Beersheba,
- Rambam Health Care Campus โ Haifa,
- Hadassah University Hospital - Ein Kerem โ Jerusalem,
- Center Hospital โ Ramat Gan,
- Sourasky Medical Center โ Tel Aviv,
- IRCCS Azienda Ospedaliero Universitaria di Bologna โ Bologna, Emilia-Romagna
- IRCCS Istituto Romagnolo per lo studio dei tumori "Dino Amadori" โ Meldola, Emilia-Romagna
- Irccs Ospedale San Raffaele โ Milan, Lombardy
- Azienda Ospedaliero Universitaria Pisana-Ospedale Santa Chia โ Pisa, Piedmont
- ICO L'Hospitalet โ L'Hospitalet de Llobregat, Barcelona
- Hospital Universitario La Fe โ Valencia, Valencia
- Hospital Universitari Vall d Hebron โ Barcelona,
- Clinica Universidad de Navarra-Madrid โ Madrid,
- Hospital General Universitario Gregorio Maranon โ Madrid,
- Hosp Universitario Salamanca โ Salamanca,
- NHS Greater Glasgow and Clyde โ Glasgow,
- University College London Hospitals โ London,
- Nottingham University Hospitals City Campus โ Nottingham,
- Oxford University Hospitals NHS Trust - Churchill Hospital โ Oxford,
๐ Contact the Study Coordinator
Phone: (877) 827-3222
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Non-Hodgkin Lymphoma
- A Study Evaluating Efficacy and Safety of Mosunetuzumab in Combination With Polatuzumab Vedotin Compared to Rituximab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma โ Duarte, California
- A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab in Combination With Oral and Intravenous Anti-Neoplastic Agents in Adult Participants With Non-Hodgkin Lymphoma โ Tucson, Arizona
- A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab Monotherapy in Participants With Select B-Cell Malignancies โ Mobile, Alabama
- AntiCD19 Chimeric Antigen Receptor T Cells for Relapsed or Refractory Non Hodgkin Lymphoma โ St Louis, Missouri
- Radiation Dose Study for Relapsed/Refractory Hodgkin/Non-Hodgkin Lymphoma โ Chicago, Illinois
- Duvelisib Following Chimeric Antigen Receptor T-Cell Therapy โ St Louis, Missouri
Explore by condition: All Non-Hodgkin Lymphoma clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.