๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-14

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma (NCT05169515)

A Phase Ib, Open-Label, Multicenter Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Patients With B-Cell Non-Hodgkin Lymphoma

๐Ÿ”ต Active, Not Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Hoffmann-La Roche

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This study will evaluate the safety, efficacy, and pharmacokinetics of mosunetuzumab or glofitamab in combination with CELMoDs (CC-220 and/or CC-99282) in participants with B-cell NHL.

Who can join: Review the eligibility criteria below.

Location: UCSF/Hematology, Blood & Marrow Transplant, And Cellular Therapy (HBC) Program โ€” San Francisco, California

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (25 Sites)

  • UCSF/Hematology, Blood & Marrow Transplant, And Cellular Therapy (HBC) Program โ€” San Francisco, California
  • University of Colorado โ€” Aurora, Colorado
  • Moffitt Cancer Center โ€” Tampa, Florida
  • The University of Chicago โ€” Chicago, Illinois
  • Levine Cancer Institute โ€” Charlotte, North Carolina
  • UT MD Anderson Cancer Center โ€” Houston, Texas
  • Soroka โ€” Beersheba,
  • Rambam Health Care Campus โ€” Haifa,
  • Hadassah University Hospital - Ein Kerem โ€” Jerusalem,
  • Center Hospital โ€” Ramat Gan,
  • Sourasky Medical Center โ€” Tel Aviv,
  • IRCCS Azienda Ospedaliero Universitaria di Bologna โ€” Bologna, Emilia-Romagna
  • IRCCS Istituto Romagnolo per lo studio dei tumori "Dino Amadori" โ€” Meldola, Emilia-Romagna
  • Irccs Ospedale San Raffaele โ€” Milan, Lombardy
  • Azienda Ospedaliero Universitaria Pisana-Ospedale Santa Chia โ€” Pisa, Piedmont
  • ICO L'Hospitalet โ€” L'Hospitalet de Llobregat, Barcelona
  • Hospital Universitario La Fe โ€” Valencia, Valencia
  • Hospital Universitari Vall d Hebron โ€” Barcelona,
  • Clinica Universidad de Navarra-Madrid โ€” Madrid,
  • Hospital General Universitario Gregorio Maranon โ€” Madrid,
  • Hosp Universitario Salamanca โ€” Salamanca,
  • NHS Greater Glasgow and Clyde โ€” Glasgow,
  • University College London Hospitals โ€” London,
  • Nottingham University Hospitals City Campus โ€” Nottingham,
  • Oxford University Hospitals NHS Trust - Churchill Hospital โ€” Oxford,

๐Ÿ“ž Contact the Study Coordinator

Phone: (877) 827-3222

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—