๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-01-13

PERSEVERE- A Trial to Evaluate AMDS in Acute DeBakey Type I Dissection (NCT05174767)

A ProspEctive, Single ARm, Multi-center Clinical InveStigation to EValuatE the Safety and Effectiveness of AMDS in the TREatment of Acute DeBakey Type I Dissection: PERSEVERE

๐Ÿ”ต Active, Not Recruiting Observational / Diagnostic โš™๏ธ Medical Device Protocol Sponsor: Artivion Inc.

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

Prospective, non-randomized, multicenter clinical investigation to assess the safety and effectiveness of AMDS in the treatment of patients with acute DeBakey type I dissection, with evidence of malperfusion, through open surgical repair.

Who can join: Review the eligibility criteria below.

Location: University of Alabama at Birmingham โ€” Birmingham, Alabama

Age range: 18 Years to 80 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (25 Sites)

  • University of Alabama at Birmingham โ€” Birmingham, Alabama
  • University of Southern California โ€” Los Angeles, California
  • Stanford University โ€” Palo Alto, California
  • University of Colorado โ€” Aurora, Colorado
  • Hartford Hospital โ€” Hartford, Connecticut
  • University of Florida โ€” Gainesville, Florida
  • Emory University Medical Center โ€” Atlanta, Georgia
  • Northwestern University โ€” Chicago, Illinois
  • Massachusetts General Hospital โ€” Boston, Massachusetts
  • University of Michigan โ€” Ann Arbor, Michigan
  • Washington University in St. Louis โ€” St Louis, Missouri
  • Mount Sinai Hospital โ€” New York, New York
  • Columbia University Irving Medical Center/New York Presbyterian Hospital โ€” New York, New York
  • Northwell โ€” New York, New York
  • Montefiore Einstein Medical โ€” The Bronx, New York
  • Atrium Health Carolinas Medical Center โ€” Charlotte, North Carolina
  • Cleveland Clinic Foundation โ€” Cleveland, Ohio
  • Oregon Health and Science University โ€” Portland, Oregon
  • University of Pennsylvania โ€” Philadelphia, Pennsylvania
  • University of Pittsburgh Medical Center โ€” Pittsburgh, Pennsylvania
  • Lankenau Medical Center โ€” Wynnewood, Pennsylvania
  • Medical University of South Carolina โ€” Charleston, South Carolina
  • Ascension Seton/University of Texas โ€” Austin, Texas
  • Baylor College of Medicine/ St. Luke's Medical Center โ€” Houston, Texas
  • Baylor Scott & White The Heart Hospital Plano โ€” Plano, Texas

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

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๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—