Genetic and Cognitive Predictors of Aphasia Treatment Response (NCT05179538)
Laying the Groundwork for Personalized Medicine in Aphasia Therapy: Genetic and Cognitive Predictors of Restorative Treatment Response
🩺 Plain-English Summary (8th-Grade Level)
Aphasia, or language impairment after a stroke, affects approximately 2 million people in the United States, with an estimated 180,000 new cases each year. The medical community cannot predict how well someone with aphasia will respond to treatment, as some people with aphasia are poor responders to intervention even when participating in empirically supported treatments. There is a strong likelihood that genetics play a role in language recovery after stroke, but very little research has been dedicated to investigating this link. This study will investigate whether two genes and cognitive abilities, such as memory, predict responsiveness to aphasia therapy for word-retrieval difficulties.
Who can join: Review the eligibility criteria below.
Location: The Ohio State University — Columbus, Ohio
Age range: 18 Years to 85 Years
🧪 Interventions in This Study
- Cued picture-naming therapy (BEHAVIORAL)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- The Ohio State University — Columbus, Ohio
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Aphasia
- Semantic Feature Analysis Treatment for Aphasia — Pittsburgh, Pennsylvania
- Treatment Outcomes With tDCS in Post-Stroke Aphasia — Little Rock, Arkansas
- Brain-based Understanding of Individual Language Differences After Stroke — Washington D.C., District of Columbia
- HD-tDCS for Phonological Impairment in Aphasia — Milwaukee, Wisconsin
- Effects of Semantic Context on Criterion-learning Naming Treatment in Aphasia — Elkins Park, Pennsylvania
Explore by condition: All Aphasia clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.