🏛️ Verified NIH Record • Updated 2025-11-27
Endometrial Cancer Patientes MMR Deficient Comparing Chemotherapy vs Dostarlimab in First Line (NCT05201547)
Randomized Phase III Trial in MMR Deficient Endometrial Cancer Patients Comparing Chemotherapy Alone Versus Dostarlimab in First Line Advanced/Metastatic Setting
🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: ARCAGY/ GINECO GROUP
🩺 Plain-English Summary (8th-Grade Level)
Phase 3, randomized, multicentre study to evaluate the efficacy and safety of dostarlimab versus carboplatin-paclitaxel in patients with MMR deficient relapse or advanced endometrial cancer.
Who can join: Review the eligibility criteria below.
Location: Canberra Hospital — Garran
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (100 Sites)
Showing the first 25 of 100 sites.
- Canberra Hospital — Garran,
- Calvary Mater Newcastle — Waratah,
- Princess Margaret Cancer Centre — Toronto,
- CHU d'Amiens - Hôpital Sud — Amiens,
- Clinique de l'Europe — Amiens,
- ICO Paul Papin — Angers,
- Centre Hospitalier d'Auxerre — Auxerre,
- Institut Sainte Catherine — Avignon,
- CH Simone Veil de Beauvais — Beauvais,
- CHRU Jean Minjoz — Besançon,
- Institut Bergonié — Bordeaux,
- CHU Brest — Brest,
- Centre François Baclesse — Caen,
- Centre Hospitalier William Morey — Chalon-sur-Saône,
- ROC 37 — Chambray-lès-Tours,
- Centre Jean Perrin — Clermont-Ferrand,
- GHPSO — Creil,
- Centre Hospitalier Intercommunal de Créteil — Créteil,
- Centre Georges François Leclerc — Dijon,
- CHU de Dijon — Dijon,
- Clinique Victor Hugo — Le Mans,
- Centre Oscar Lambret — Lille,
- Centre Hospitalier Lyon Sud — Lyon,
- Centre Léon Bérard — Lyon,
- APHM - Hôpital de la Timone — Marseille,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- Phase 2 Study Evaluating the Efficacy of the Combination of DKN-01 (DKK1 Inhibitor, Leap Therapeutics) and Pembrolizumab in the Treatment of Advanced or Recurrent Endometrial Cancer — Houston, Texas
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Explore by condition: All Endometrial Cancer clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.